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Pharmacokinetic Effect of AMD070, an Oral CXCR4 Antagonist, on CYP3A4 and CYP2D6 Substrates Midazolam and Dextromethorphan in Healthy Volunteers

Author
NYUNT, Myaing M1 ; BECKER, Stephen2 ; MACFARLAND, Ron T3 ; CHEE, Priscilla3 ; SCARBOROUGH, Robert3 ; EVERTS, Stephanie1 ; CALANDRA, Gary B3 ; HENDRIX, Craig W1
[1] Johns Hopkins University School of Medicine, Division of Clinical Pharmacology, Baltimore, MD, United States
[2] Koronis Pharmaceuticals, Redmond, WA, United States
[3] AnorMED, Langley, British Columbia, Canada
Source

Journal of acquired immune deficiency syndromes (1999). 2008, Vol 47, Num 5, pp 559-565, 7 p ; ref : 31 ref

ISSN
1525-4135
Scientific domain
Immunology, immunopathology, allergology; Virology
Publisher
Lippincott Williams & Wilkins, Hagerstown, MD
Publication country
United States
Document type
Article
Language
English
Author keyword
AMD070 CXCR4 inhibitor CYP2D6 CYP3A4 drug interaction
Keyword (fr)
Dextrométhorphane Microbiologie Midazolam Récepteur chimiokine CXCR4 Virologie
Keyword (en)
Dextromethorphan Microbiology Midazolam CXCR4 chemokine receptor Virology
Keyword (es)
Dextrometorfano Microbiología Midazolam Receptor quimioquina CXCR4 Virología
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A05 Microbiology / 002A05C Virology / 002A05C10 Miscellaneous

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B05 Infectious diseases / 002B05C Viral diseases / 002B05C02 Human viral diseases / 002B05C02J Miscellaneous

Discipline
Infectious pathology Microbiology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20264395

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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