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Secondary mutations in the kinase domain of the KIT gene are predominant in imatinib-resistant gastrointestinal stromal tumor

Author
NISHIDA, Toshirou1 ; KANDA, Tatsuo2 ; NISHITANI, Akiko1 ; TAKAHASHI, Tsuyoshi1 ; NAKAJIMA, Kiyokazu1 ; ISHIKAWA, Takashi2 ; HIROTA, Seiichi3
[1] Department of Surgery, Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita 565-0871, Osaka, Japan
[2] Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-duri, Niigata 951-8510, Japan
[3] Department of Surgical Pathology, Hyogo College of Medicine, 1-1 Mukogwa-cho, Nishinomiya, 663-8501, Hyogo, Japan
Source

Cancer science. 2008, Vol 99, Num 4, pp 799-804, 6 p ; ref : 26 ref

ISSN
1347-9032
Scientific domain
Medical oncology
Publisher
Blackwell, Tokyo
Publication country
Japan
Document type
Article
Language
English
Keyword (fr)
Anticancéreux Cancérologie Gène kit Génétique Imatinib Inhibiteur enzyme Kinase Mutation Protein-tyrosine kinase Résistance Secondaire Tumeur stromale gastrointestinale Cancer Enzyme Inhibiteur de la tyrosine kinase Pathologie de l'appareil digestif Pathologie de l'estomac Transferases Tumeur maligne
Keyword (en)
Antineoplastic agent Cancerology kit Gene Genetics Imatinib Enzyme inhibitor Kinase Mutation Protein-tyrosine kinase Resistance Secondary Gastrointestinal stromal tumor Cancer Enzyme Tyrosine kinase inhibitor Digestive diseases Gastric disease Transferases Malignant tumor
Keyword (es)
Anticanceroso Cancerología Gen kit Genética Imatinib Inhibidor enzima Kinase Mutación Protein-tyrosine kinase Resistencia Secundario Tumor estromal gastrointestinal Cáncer Enzima Inhibidor tyrosine kinase Aparato digestivo patología Estómago patología Transferases Tumor maligno
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13B Stomach. Duodenum. Small intestine. Colon. Rectum. Anus / 002B13B01 Tumors

Discipline
Gastroenterology. Liver. Pancreas. Abdomen Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20271792

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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