Phospholipase C-β1 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration
- Author
- MCOMISH, C. E1 ; BURROWS, E1 ; HOWARD, M1 ; SCARR, E2 3 ; KIM, D4 ; SHIN, H.-S4 ; DEAN, B2 5 6 ; VAN DEN BUUSE, M2 ; HANNAN, A. J1
[1] Howard Florey Institute, University of Melbourne, Melbourne, VIC, Australia
[2] Mental Health Research Institute of Victoria, Melbourne, VIC, Australia
[3] Centre for Neuroscience, University of Melbourne, Parkville, VIC, Australia
[4] Centre for Calcium and Learning, Korea Institute of Science and Technology, Seoul, Korea, Republic of
[5] Department of Pathology, University of Melbourne, Melbourne, VIC, Australia
[6] Department of Psychiatry, University of Melbourne, Melbourne, VIC, Australia - Source
Molecular psychiatry. 2008, Vol 13, Num 7, pp 661-672, 12 p ; ref : 72 ref
- ISSN
- 1359-4184
- Scientific domain
- Biochemistry, molecular biology, biophysics; Psychology, psychopathology, psychiatry
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- antipsychotics clozapine environmental enrichment haloperidol muscarinic receptors schizophrenia
- Keyword (fr)
- Animal Antipsychotique atypique Clozapine Endophénotype Environnement stimulant Halopéridol Mutation Neuroleptique Pharmacothérapie Phospholipase C Récepteur muscarinique Schizophrénie Souris Dérivé de la dibenzodiazépine Antagoniste dopamine Dérivé de la butyrophénone Enzyme Esterases Hydrolases Mammalia Phosphoric diester hydrolases Psychose Psychotrope Rodentia Récepteur cholinergique Récepteur dopaminergique D2 Traitement Vertebrata
- Keyword (en)
- Animal Atypical antipsychotic Clozapine Endophenotype Stimulating environment Haloperidol Mutation Neuroleptic Pharmacotherapy Phospholipase C Muscarinic receptor Schizophrenia Mouse Dopamine antagonist Butyrophenone derivatives Enzyme Esterases Hydrolases Mammalia Phosphoric diester hydrolases Psychosis Psychotropic Rodentia Cholinergic receptor D2 Dopamine receptor Treatment Vertebrata
- Keyword (es)
- Animal Antipsicótico atípico Clozapina Endofenotipo Medio ambiente estimulante Haloperidol Mutación Neuroléptico Farmacoterapia Phospholipase C Receptor muscarínico Esquizofrenia Ratón Antagonista dopamina Butirofenona derivado Enzima Esterases Hydrolases Mammalia Phosphoric diester hydrolases Psicosis Psicotropo Rodentia Receptor colinérgico Receptor dopaminérgico D2 Tratamiento Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B03 Psycholeptics: tranquillizer, neuroleptic.
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B18 Psychopathology. Psychiatry / 002B18C Adult and adolescent clinical studies / 002B18C06 Psychoses / 002B18C06A Schizophrenia
- Francis
- 770 Psychology. Psychoanalysis. Psychiatry / 770-D Psychopathology. Psychiatry / 770-D03 Adult and adolescent clinical studies / 770-D03F Psychoses / 770-D03F01 Schizophrenia
- Francis
- 770 Psychology. Psychoanalysis. Psychiatry / 770-E Psychopharmacology / 770-E03 Psycholeptics: tranquillizer, neuroleptic…
- Discipline
- Pharmacological treatments Psychopathology. Psychiatry. Clinical psychology
- Origin
- Inist-CNRS
- Database
- FRANCIS ; PASCAL
- INIST identifier
- 20439359
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
Access to the document
Install on your browser
DOI
10.1038/sj.mp.4002046 
https://dx.doi.org/10.1038/sj.mp.4002046
"O:13:\"PanistOpenUrl\":36:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000idc\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:21:\"10.1038\/sj.mp.4002046\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:154:\"Phospholipase C-\u03b21 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration\";s:9:\"\u0000*\u0000jtitle\";s:20:\"Molecular psychiatry\";s:9:\"\u0000*\u0000stitle\";s:15:\"Mol. psychiatry\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:2:\"13\";s:8:\"\u0000*\u0000issue\";s:1:\"7\";s:8:\"\u0000*\u0000spage\";s:3:\"661\";s:8:\"\u0000*\u0000epage\";s:3:\"672\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"1359-4184\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:7:\"MCOMISH\";s:10:\"\u0000*\u0000aufirst\";s:4:\"C. E\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:10:\"BURROWS, E\";i:1;s:9:\"HOWARD, M\";i:2;s:8:\"SCARR, E\";i:3;s:6:\"KIM, D\";i:4;s:10:\"SHIN, H.-S\";i:5;s:7:\"DEAN, B\";i:6;s:16:\"VAN DEN BUUSE, M\";i:7;s:12:\"HANNAN, A. J\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:154:\"Phospholipase C-\u03b21 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration\";s:8:\"\u0000*\u0000place\";s:11:\"Basingstoke\";s:6:\"\u0000*\u0000pub\";s:23:\"Nature Publishing Group\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"12\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Panist access
"O:12:\"IstexOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:21:\"10.1038\/sj.mp.4002046\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:154:\"Phospholipase C-\u03b21 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration\";s:9:\"\u0000*\u0000jtitle\";s:20:\"Molecular psychiatry\";s:9:\"\u0000*\u0000stitle\";s:15:\"Mol. psychiatry\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:2:\"13\";s:8:\"\u0000*\u0000issue\";s:1:\"7\";s:8:\"\u0000*\u0000spage\";s:3:\"661\";s:8:\"\u0000*\u0000epage\";s:3:\"672\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"1359-4184\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:7:\"MCOMISH\";s:10:\"\u0000*\u0000aufirst\";s:4:\"C. E\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:10:\"BURROWS, E\";i:1;s:9:\"HOWARD, M\";i:2;s:8:\"SCARR, E\";i:3;s:6:\"KIM, D\";i:4;s:10:\"SHIN, H.-S\";i:5;s:7:\"DEAN, B\";i:6;s:16:\"VAN DEN BUUSE, M\";i:7;s:12:\"HANNAN, A. J\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:154:\"Phospholipase C-\u03b21 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration\";s:8:\"\u0000*\u0000place\";s:11:\"Basingstoke\";s:6:\"\u0000*\u0000pub\";s:23:\"Nature Publishing Group\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"12\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Istex access
"O:16:\"UnpaywallOpenUrl\":35:{s:8:\"\u0000*\u0000email\";s:27:\"assistance-portail@inist.fr\";s:6:\"\u0000*\u0000fmt\";N;s:6:\"\u0000*\u0000doi\";s:21:\"10.1038\/sj.mp.4002046\";s:6:\"\u0000*\u0000pii\";N;s:7:\"\u0000*\u0000pmid\";N;s:9:\"\u0000*\u0000atitle\";N;s:9:\"\u0000*\u0000jtitle\";N;s:9:\"\u0000*\u0000stitle\";N;s:7:\"\u0000*\u0000date\";N;s:9:\"\u0000*\u0000volume\";N;s:8:\"\u0000*\u0000issue\";N;s:8:\"\u0000*\u0000spage\";N;s:8:\"\u0000*\u0000epage\";N;s:8:\"\u0000*\u0000pages\";N;s:7:\"\u0000*\u0000issn\";N;s:8:\"\u0000*\u0000eissn\";N;s:9:\"\u0000*\u0000aulast\";N;s:10:\"\u0000*\u0000aufirst\";N;s:9:\"\u0000*\u0000auinit\";N;s:10:\"\u0000*\u0000auinitm\";N;s:5:\"\u0000*\u0000au\";N;s:9:\"\u0000*\u0000aucorp\";N;s:7:\"\u0000*\u0000isbn\";N;s:8:\"\u0000*\u0000coden\";N;s:8:\"\u0000*\u0000genre\";N;s:7:\"\u0000*\u0000part\";N;s:9:\"\u0000*\u0000btitle\";N;s:8:\"\u0000*\u0000title\";N;s:8:\"\u0000*\u0000place\";N;s:6:\"\u0000*\u0000pub\";N;s:10:\"\u0000*\u0000edition\";N;s:9:\"\u0000*\u0000tpages\";N;s:9:\"\u0000*\u0000series\";N;s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";N;}"
Unpaywall access
"O:16:\"EuropePMCOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:21:\"10.1038\/sj.mp.4002046\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:154:\"Phospholipase C-\u03b21 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration\";s:9:\"\u0000*\u0000jtitle\";s:20:\"Molecular psychiatry\";s:9:\"\u0000*\u0000stitle\";s:15:\"Mol. psychiatry\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:2:\"13\";s:8:\"\u0000*\u0000issue\";s:1:\"7\";s:8:\"\u0000*\u0000spage\";s:3:\"661\";s:8:\"\u0000*\u0000epage\";s:3:\"672\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"1359-4184\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:7:\"MCOMISH\";s:10:\"\u0000*\u0000aufirst\";s:4:\"C. E\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:10:\"BURROWS, E\";i:1;s:9:\"HOWARD, M\";i:2;s:8:\"SCARR, E\";i:3;s:6:\"KIM, D\";i:4;s:10:\"SHIN, H.-S\";i:5;s:7:\"DEAN, B\";i:6;s:16:\"VAN DEN BUUSE, M\";i:7;s:12:\"HANNAN, A. J\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:154:\"Phospholipase C-\u03b21 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration\";s:8:\"\u0000*\u0000place\";s:11:\"Basingstoke\";s:6:\"\u0000*\u0000pub\";s:23:\"Nature Publishing Group\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"12\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Europe PubMed Central access
"O:11:\"BaseOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:21:\"10.1038\/sj.mp.4002046\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:154:\"Phospholipase C-\u03b21 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration\";s:9:\"\u0000*\u0000jtitle\";s:20:\"Molecular psychiatry\";s:9:\"\u0000*\u0000stitle\";s:15:\"Mol. psychiatry\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:2:\"13\";s:8:\"\u0000*\u0000issue\";s:1:\"7\";s:8:\"\u0000*\u0000spage\";s:3:\"661\";s:8:\"\u0000*\u0000epage\";s:3:\"672\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"1359-4184\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:7:\"MCOMISH\";s:10:\"\u0000*\u0000aufirst\";s:4:\"C. E\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:10:\"BURROWS, E\";i:1;s:9:\"HOWARD, M\";i:2;s:8:\"SCARR, E\";i:3;s:6:\"KIM, D\";i:4;s:10:\"SHIN, H.-S\";i:5;s:7:\"DEAN, B\";i:6;s:16:\"VAN DEN BUUSE, M\";i:7;s:12:\"HANNAN, A. J\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:154:\"Phospholipase C-\u03b21 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration\";s:8:\"\u0000*\u0000place\";s:11:\"Basingstoke\";s:6:\"\u0000*\u0000pub\";s:23:\"Nature Publishing Group\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"12\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Base Search access
"O:12:\"ArXivOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:21:\"10.1038\/sj.mp.4002046\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:154:\"Phospholipase C-\u03b21 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration\";s:9:\"\u0000*\u0000jtitle\";s:20:\"Molecular psychiatry\";s:9:\"\u0000*\u0000stitle\";s:15:\"Mol. psychiatry\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:2:\"13\";s:8:\"\u0000*\u0000issue\";s:1:\"7\";s:8:\"\u0000*\u0000spage\";s:3:\"661\";s:8:\"\u0000*\u0000epage\";s:3:\"672\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"1359-4184\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:7:\"MCOMISH\";s:10:\"\u0000*\u0000aufirst\";s:4:\"C. E\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:10:\"BURROWS, E\";i:1;s:9:\"HOWARD, M\";i:2;s:8:\"SCARR, E\";i:3;s:6:\"KIM, D\";i:4;s:10:\"SHIN, H.-S\";i:5;s:7:\"DEAN, B\";i:6;s:16:\"VAN DEN BUUSE, M\";i:7;s:12:\"HANNAN, A. J\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:154:\"Phospholipase C-\u03b21 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration\";s:8:\"\u0000*\u0000place\";s:11:\"Basingstoke\";s:6:\"\u0000*\u0000pub\";s:23:\"Nature Publishing Group\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:2:\"12\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
arXiv access
