Targeting QseC Signaling and Virulence for Antibiotic Development
- Author
- RASKO, David A1 ; MOREIRA, Cristiano G1 ; HUGHES, David T1 ; HUNTLEY, Jason F1 ; FINA, Maggy W4 ; FALCK, John R2 4 ; SPERANDIO, Vanessa1 2 ; DE RUN LI2 ; READING, Nicola C1 ; RITCHIE, Jennifer M3 ; WALDOR, Matthew K3 ; WILLIAMS, Noelle2 ; TAUSSIG, Ron4 ; SHUGUANG WEI2 ; ROTH, Michael2
[1] Department of Microbiology, University of Texas (UT) Southwestern Medical Center, Dallas, TX 75390, United States
[2] Department of Biochemistry, University of Texas (UT) Southwestern Medical Center, Dallas, TX 75390, United States
[3] Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, United States
[4] Department of Pharmacology, University of Texas (UT) Southwestern Medical Center, Dallas, TX 75390, United States - Source
Science (Washington, D.C.). 2008, Vol 321, Num 5892, pp 1078-1080, 3 p ; ref : 19 ref
- CODEN
- SCIEAS
- ISSN
- 0036-8075
- Scientific domain
- Multidisciplinary
- Publisher
- American Association for the Advancement of Science, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Antibactérien Antibiotique Antimicrobien Criblage haut débit Escherichia coli Expression génique Francisella tularensis Non-specific serine/threonine protein kinase Recherche et développement Salmonella typhimurium Transduction signal Virulence Histidine sensor kinase LED 209 Protein-histidine kinase Bactérie Enterobacteriaceae Enzyme Transferases
- Keyword (en)
- Antibacterial agent Antibiotic Antimicrobial agent High throughput screening Escherichia coli Gene expression Francisella tularensis Non-specific serine/threonine protein kinase Research and development Salmonella typhimurium Signal transduction Virulence Bacteria Enterobacteriaceae Enzyme Transferases
- Keyword (es)
- Antibacteriano Antibiótico Antimicrobiano Cribado alta productividad Escherichia coli Expresión genética Francisella tularensis Non-specific serine/threonine protein kinase Investigación desarrollo Salmonella typhimurium Transducción señal Virulencia Bacteria Enterobacteriaceae Enzima Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S02 Antibacterial agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20616328
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1126/science.1160354 
https://dx.doi.org/10.1126/science.1160354
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