Hyperphosphorylation of Microtubule-Associated Protein Tau : A Promising Therapeutic Target for Alzheimer Disease
- Author
- GONG, C.-X1 ; IQBAL, K1
[1] Department of Neurochemistry, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, New York, United States - Source
Current medicinal chemistry. 2008, Vol 15, Num 23, pp 2321-2328, 8 p ; ref : 141 ref
- ISSN
- 0929-8673
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Bentham Science, Oak Park, IL
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- Alzheimer disease GSK-3β O-GlcNAcylation cdk5 neurodegeneration protein phosphatases tau therapy
- Keyword (fr)
- Dégénérescence Démence d'Alzheimer Glycosylation Kinase cycline dépendante Maladie dégénérative Pathogénie Pathologie du système nerveux Phosphoprotein phosphatase Protéine tau Structure neurofibrillaire Tau-protein kinase Traitement Transduction signal EC 2-7-11-26 Enzyme Esterases Hydrolases Pathologie de l'encéphale Phosphoric monoester hydrolases Transferases
- Keyword (en)
- Degeneration Alzheimer disease Glycosylation Cyclin dependent kinase Degenerative disease Pathogenesis Nervous system diseases Phosphoprotein phosphatase Tau protein Neurofibrillary tangle Tau-protein kinase Treatment Signal transduction Enzyme Esterases Hydrolases Cerebral disorder Phosphoric monoester hydrolases Transferases
- Keyword (es)
- Degeneración Demencia Alzheimer Glicosilación Cyclin dependent kinase Enfermedad degenerativa Patogenia Sistema nervioso patología Phosphoprotein phosphatase Proteína tau Estructura neurofibrilar Tau-protein kinase Tratamiento Transducción señal Enzima Esterases Hydrolases Encéfalo patología Phosphoric monoester hydrolases Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B02 Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Francis
- 770 Psychology. Psychoanalysis. Psychiatry / 770-E Psychopharmacology / 770-E02 Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer…
- Discipline
- Neurology Pharmacological treatments Psychopathology. Psychiatry. Clinical psychology
- Origin
- Inist-CNRS
- Database
- FRANCIS ; PASCAL
- INIST identifier
- 20632431
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.2174/092986708785909111 
https://dx.doi.org/10.2174/092986708785909111
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