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On the use of lonafarnib in myelodysplastic syndrome and chronic myelomonocytic leukemia

Author
FELDMAN, E. J1 ; CORTES, J2 ; MALOISEL, F10 ; COLOMBAT, P11 ; MARTINELLI, G12 ; NIELSEN, J. L13 ; PETERSDORF, S14 ; GUILHOT, F15 ; BARKER, J16 ; KIRSCHMEIER, P17 ; FRANK, E17 ; STATKEVICH, P17 ; DEANGELO, D. J3 ; ZHU, Y17 ; LOECHNER, S17 ; LIST, A18 ; HOLYOAKE, T4 ; SIMONSSON, B5 ; O'BRIEN, S. G6 ; REIFFERS, J7 ; TURNER, A. R8 ; ROBOZ, G. J1 ; LIPTON, J. H9
[1] Division of Hematology and Medical Oncology, Weill-Cornel Medical College, New York, NY, United States
[2] Department of Leukemia, MD Anderson Cancer Center, Houston, TX, United States
[3] Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, United States
[4] Division of Cancer and Molecular Pathology, Glasgow Royal Infirmary, Glasgow, United Kingdom
[5] Department of Hematology, University Hospital, Uppsala, Sweden
[6] Department of Hematology, Newcastle University, Newcastle upon Tyne, United Kingdom
[7] Institut Bergonie and Universite Victor Segalen, Bordeaux, France
[8] Division of Medical Oncology, Cross Cancer Institute, Edmonton, Canada
[9] Division of Medical Oncology and Hematology and Oncology, Princess Margaret Hospital, Ontario, Canada
[10] Department of Hematologie-Oncologie, Hopitaux Universitaires de Strasbourg, Strasbourg, France
[11] Department of Hematology, CHU Tours, France
[12] Department of Hematology/Oncology, Universita' di Bologna, Bologna, Italy
[13] Department of Hematology, University Hospital, Arhus, Denmark
[14] Division of Medical Oncology, Seattle Cancer Care Alliance, Seattle, WA, United States
[15] Department of Oncology-Haematology and Cell therapeutics, CIC INSERM 802 C.H.U. de Poitiers, Poitiers, France
[16] Department of Hematology, University of Minnesota, Minneapolis, MN, United States
[17] Schering-Plough Research Institute, Kenilworth, NJ, United States
[18] Malignant Hematology Division, H. Lee Moffit Cancer Center and Research Institute, Tampa, FL, United States
Source

Leukemia. 2008, Vol 22, Num 9, pp 1707-1711, 5 p ; ref : 23 ref

CODEN
LEUKED
ISSN
0887-6924
Scientific domain
Medical oncology; Hematology
Publisher
Nature Publishing, London
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
CMML Ionafarnib MDS
Keyword (fr)
Anticancéreux Cancérologie Chimiothérapie Efficacité traitement Farnesyltranstransferase Homme Hématologie Inhibiteur enzyme Lonafarnib Stade avancé Syndrome myélodysplasique Leucemie myélomonocytaire chronique Pharmacodynamie Cancer Enzyme Hémopathie maligne Syndrome myéloprolifératif Traitement Transferases
Keyword (en)
Antineoplastic agent Cancerology Chemotherapy Treatment efficiency Farnesyltranstransferase Human Hematology Enzyme inhibitor Lonafarnib Advanced stage Myelodysplastic syndrome Chronic myelomonocytic leukemia Pharmacodynamics Cancer Enzyme Malignant hemopathy Myeloproliferative syndrome Treatment Transferases
Keyword (es)
Anticanceroso Cancerología Quimioterapia Eficacia tratamiento Farnesyltranstransferase Hombre Hematología Inhibidor enzima Lonafarnib Estadio avanzado Mielodisplastico síndrome Leucemia mielomonocitaria cronica Farmacodinámica Cáncer Enzima Hemopatía maligna Mieloproliferativo síndrome Tratamiento Transferases
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R02 Chemotherapy

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis

Discipline
Blood diseases Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20666661

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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