Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease
- Author
- BUSCHE, Marc Aurel1 2 ; EICHHOFF, Gerhard1 2 ; ADELSBERGER, Helmuth1 2 ; ABRAMOWSKI, Dorothee3 ; WIEDERHOLD, Karl-Heinz3 ; HAASS, Christian2 4 ; STAUFENBIEL, Matthias3 ; KONNERTH, Arthur1 2 ; GARASCHUK, Olga1 2
[1] Institut für Neurowissenschaften, Technische Universität München (TUM), 80802 München, Germany
[2] Center for Integrated Protein Science, 81377 München, Germany
[3] Novartis Institutes for Biomedical Research, 4002 Basel, Switzerland
[4] Adolf-Butenandt-lnstitute, Department of Biochemistry, Laboratory for Neurodegenerative Disease Research, Ludwig-Maximilians-Universität, 80336 München, Germany - Source
Science (Washington, D.C.). 2008, Vol 321, Num 5896, pp 1686-1689, 4 p
- CODEN
- SCIEAS
- ISSN
- 0036-8075
- Scientific domain
- Multidisciplinary
- Publisher
- American Association for the Advancement of Science, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Amyloïde Animal Calcium Dégénérescence Démence d'Alzheimer Formation image Modèle animal Neurone Photon Protéine amyloïde β Souris Maladie dégénérative Mammalia Pathologie du système nerveux Rodentia Vertebrata
- Keyword (en)
- Amyloid Animal Calcium Degeneration Alzheimer disease Imaging Animal model Neuron Photon β Amyloid protein Mouse Degenerative disease Mammalia Nervous system diseases Rodentia Vertebrata
- Keyword (es)
- Amiloide Animal Calcio Degeneración Demencia Alzheimer Formación imagen Modelo animal Neurona Fotón Proteína amiloide β Ratón Enfermedad degenerativa Mammalia Sistema nervioso patología Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Discipline
- Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20680255
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
Access to the document
Install on your browser
DOI
10.1126/science.1162844 
https://dx.doi.org/10.1126/science.1162844
"O:13:\"PanistOpenUrl\":36:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000idc\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:23:\"10.1126\/science.1162844\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:92:\"Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease\";s:9:\"\u0000*\u0000jtitle\";s:26:\"Science (Washington, D.C.)\";s:9:\"\u0000*\u0000stitle\";s:20:\"Science (Wash. D.C.)\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:3:\"321\";s:8:\"\u0000*\u0000issue\";s:4:\"5896\";s:8:\"\u0000*\u0000spage\";s:4:\"1686\";s:8:\"\u0000*\u0000epage\";s:4:\"1689\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0036-8075\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:6:\"BUSCHE\";s:10:\"\u0000*\u0000aufirst\";s:10:\"Marc Aurel\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:17:\"EICHHOFF, Gerhard\";i:1;s:20:\"ADELSBERGER, Helmuth\";i:2;s:20:\"ABRAMOWSKI, Dorothee\";i:3;s:22:\"WIEDERHOLD, Karl-Heinz\";i:4;s:16:\"HAASS, Christian\";i:5;s:21:\"STAUFENBIEL, Matthias\";i:6;s:16:\"KONNERTH, Arthur\";i:7;s:15:\"GARASCHUK, Olga\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"SCIEAS\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:92:\"Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease\";s:8:\"\u0000*\u0000place\";s:14:\"Washington, DC\";s:6:\"\u0000*\u0000pub\";s:51:\"American Association for the Advancement of Science\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"4\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Panist access
"O:12:\"IstexOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:23:\"10.1126\/science.1162844\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:92:\"Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease\";s:9:\"\u0000*\u0000jtitle\";s:26:\"Science (Washington, D.C.)\";s:9:\"\u0000*\u0000stitle\";s:20:\"Science (Wash. D.C.)\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:3:\"321\";s:8:\"\u0000*\u0000issue\";s:4:\"5896\";s:8:\"\u0000*\u0000spage\";s:4:\"1686\";s:8:\"\u0000*\u0000epage\";s:4:\"1689\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0036-8075\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:6:\"BUSCHE\";s:10:\"\u0000*\u0000aufirst\";s:10:\"Marc Aurel\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:17:\"EICHHOFF, Gerhard\";i:1;s:20:\"ADELSBERGER, Helmuth\";i:2;s:20:\"ABRAMOWSKI, Dorothee\";i:3;s:22:\"WIEDERHOLD, Karl-Heinz\";i:4;s:16:\"HAASS, Christian\";i:5;s:21:\"STAUFENBIEL, Matthias\";i:6;s:16:\"KONNERTH, Arthur\";i:7;s:15:\"GARASCHUK, Olga\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"SCIEAS\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:92:\"Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease\";s:8:\"\u0000*\u0000place\";s:14:\"Washington, DC\";s:6:\"\u0000*\u0000pub\";s:51:\"American Association for the Advancement of Science\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"4\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Istex access
"O:16:\"UnpaywallOpenUrl\":35:{s:8:\"\u0000*\u0000email\";s:27:\"assistance-portail@inist.fr\";s:6:\"\u0000*\u0000fmt\";N;s:6:\"\u0000*\u0000doi\";s:23:\"10.1126\/science.1162844\";s:6:\"\u0000*\u0000pii\";N;s:7:\"\u0000*\u0000pmid\";N;s:9:\"\u0000*\u0000atitle\";N;s:9:\"\u0000*\u0000jtitle\";N;s:9:\"\u0000*\u0000stitle\";N;s:7:\"\u0000*\u0000date\";N;s:9:\"\u0000*\u0000volume\";N;s:8:\"\u0000*\u0000issue\";N;s:8:\"\u0000*\u0000spage\";N;s:8:\"\u0000*\u0000epage\";N;s:8:\"\u0000*\u0000pages\";N;s:7:\"\u0000*\u0000issn\";N;s:8:\"\u0000*\u0000eissn\";N;s:9:\"\u0000*\u0000aulast\";N;s:10:\"\u0000*\u0000aufirst\";N;s:9:\"\u0000*\u0000auinit\";N;s:10:\"\u0000*\u0000auinitm\";N;s:5:\"\u0000*\u0000au\";N;s:9:\"\u0000*\u0000aucorp\";N;s:7:\"\u0000*\u0000isbn\";N;s:8:\"\u0000*\u0000coden\";N;s:8:\"\u0000*\u0000genre\";N;s:7:\"\u0000*\u0000part\";N;s:9:\"\u0000*\u0000btitle\";N;s:8:\"\u0000*\u0000title\";N;s:8:\"\u0000*\u0000place\";N;s:6:\"\u0000*\u0000pub\";N;s:10:\"\u0000*\u0000edition\";N;s:9:\"\u0000*\u0000tpages\";N;s:9:\"\u0000*\u0000series\";N;s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";N;}"
Unpaywall access
"O:16:\"EuropePMCOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:23:\"10.1126\/science.1162844\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:92:\"Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease\";s:9:\"\u0000*\u0000jtitle\";s:26:\"Science (Washington, D.C.)\";s:9:\"\u0000*\u0000stitle\";s:20:\"Science (Wash. D.C.)\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:3:\"321\";s:8:\"\u0000*\u0000issue\";s:4:\"5896\";s:8:\"\u0000*\u0000spage\";s:4:\"1686\";s:8:\"\u0000*\u0000epage\";s:4:\"1689\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0036-8075\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:6:\"BUSCHE\";s:10:\"\u0000*\u0000aufirst\";s:10:\"Marc Aurel\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:17:\"EICHHOFF, Gerhard\";i:1;s:20:\"ADELSBERGER, Helmuth\";i:2;s:20:\"ABRAMOWSKI, Dorothee\";i:3;s:22:\"WIEDERHOLD, Karl-Heinz\";i:4;s:16:\"HAASS, Christian\";i:5;s:21:\"STAUFENBIEL, Matthias\";i:6;s:16:\"KONNERTH, Arthur\";i:7;s:15:\"GARASCHUK, Olga\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"SCIEAS\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:92:\"Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease\";s:8:\"\u0000*\u0000place\";s:14:\"Washington, DC\";s:6:\"\u0000*\u0000pub\";s:51:\"American Association for the Advancement of Science\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"4\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Europe PubMed Central access
"O:11:\"BaseOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:23:\"10.1126\/science.1162844\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:92:\"Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease\";s:9:\"\u0000*\u0000jtitle\";s:26:\"Science (Washington, D.C.)\";s:9:\"\u0000*\u0000stitle\";s:20:\"Science (Wash. D.C.)\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:3:\"321\";s:8:\"\u0000*\u0000issue\";s:4:\"5896\";s:8:\"\u0000*\u0000spage\";s:4:\"1686\";s:8:\"\u0000*\u0000epage\";s:4:\"1689\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0036-8075\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:6:\"BUSCHE\";s:10:\"\u0000*\u0000aufirst\";s:10:\"Marc Aurel\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:17:\"EICHHOFF, Gerhard\";i:1;s:20:\"ADELSBERGER, Helmuth\";i:2;s:20:\"ABRAMOWSKI, Dorothee\";i:3;s:22:\"WIEDERHOLD, Karl-Heinz\";i:4;s:16:\"HAASS, Christian\";i:5;s:21:\"STAUFENBIEL, Matthias\";i:6;s:16:\"KONNERTH, Arthur\";i:7;s:15:\"GARASCHUK, Olga\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"SCIEAS\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:92:\"Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease\";s:8:\"\u0000*\u0000place\";s:14:\"Washington, DC\";s:6:\"\u0000*\u0000pub\";s:51:\"American Association for the Advancement of Science\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"4\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Base Search access
"O:12:\"ArXivOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:23:\"10.1126\/science.1162844\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:92:\"Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease\";s:9:\"\u0000*\u0000jtitle\";s:26:\"Science (Washington, D.C.)\";s:9:\"\u0000*\u0000stitle\";s:20:\"Science (Wash. D.C.)\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:3:\"321\";s:8:\"\u0000*\u0000issue\";s:4:\"5896\";s:8:\"\u0000*\u0000spage\";s:4:\"1686\";s:8:\"\u0000*\u0000epage\";s:4:\"1689\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0036-8075\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:6:\"BUSCHE\";s:10:\"\u0000*\u0000aufirst\";s:10:\"Marc Aurel\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:17:\"EICHHOFF, Gerhard\";i:1;s:20:\"ADELSBERGER, Helmuth\";i:2;s:20:\"ABRAMOWSKI, Dorothee\";i:3;s:22:\"WIEDERHOLD, Karl-Heinz\";i:4;s:16:\"HAASS, Christian\";i:5;s:21:\"STAUFENBIEL, Matthias\";i:6;s:16:\"KONNERTH, Arthur\";i:7;s:15:\"GARASCHUK, Olga\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"SCIEAS\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:92:\"Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease\";s:8:\"\u0000*\u0000place\";s:14:\"Washington, DC\";s:6:\"\u0000*\u0000pub\";s:51:\"American Association for the Advancement of Science\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"4\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
arXiv access
