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DNA hypermethylation of PITX2 is a marker of poor prognosis in untreated lymph node-negative hormone receptor-positive breast cancer patients

Author
NIMMRICH, Inko1 ; SIEUWERTS, Anieta M2 ; MAGDOLEN, Viktor3 ; PORTENGEN, Henk2 ; LOOK, Maxime P2 ; KLIJN, Jan G. M2 ; LESCHE, Ralf1 ; SCHMITT, Manfred3 ; MAIER, Sabine1 ; FOEKENS, John A2 ; MARTENS, John W. M2 ; MEIJER-VAN GELDER, Marion E2 ; SCHWOPE, Ina1 ; BOLT-DE VRIES, Joan2 ; HARBECK, Nadia3 ; KOENIG, Thomas1 ; HARTMANN, Oliver1 ; KLUTH, Antje1 ; DIETRICH, Dimo1
[1] Department of Biomedical Research and Development and Technology Development, Epigenomics AG, Berlin, Germany
[2] Department of Medical Oncology, Erasmus MC, Josephine Nefkens Institute, Room Be 400, P.O. Box 2040, 3000 CA Rotterdam, Netherlands
[3] Department of Obstetrics and Gynecology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany
Source

Breast cancer research and treatment. 2008, Vol 111, Num 3, pp 429-437, 9 p ; ref : 30 ref

CODEN
BCTRD6
ISSN
0167-6806
Scientific domain
Medical oncology; Obstetrics, gynecology, andrology; Pharmacology drugs
Publisher
Springer, Dordrecht
Publication country
Netherlands
Document type
Article
Language
English
Author keyword
Breast cancer DNA-methylation Estrogen receptor PITX2 Prognosis
Keyword (fr)
Cancer du sein DNA Ganglion lymphatique Homme Marqueur biologique Méthylation Pronostic Récepteur hormonal Récepteur oestrogène Stade précoce Facteur de transcription PITX2 Cancer Pathologie de la glande mammaire Pathologie du sein Tumeur maligne
Keyword (en)
Breast cancer DNA Lymph node Human Biological marker Methylation Prognosis Hormonal receptor Estrogen receptor Early stage PITX2 transcription factor Cancer Mammary gland diseases Breast disease Malignant tumor
Keyword (es)
Cáncer del pecho DNA Ganglio linfático Hombre Marcador biológico Metilación Pronóstico Receptor hormonal Receptor estrógeno Estadio precoz Cáncer Glándula mamaria patología Seno patología Tumor maligno
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B20 Gynecology. Andrology. Obstetrics / 002B20E Mammary gland diseases / 002B20E02 Tumors

Discipline
Gynecology. Andrology. Obstetrics
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
20680646

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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