Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy
- Author
- MUNGER, Joshua1 2 ; BENNETT, Bryson D3 ; PARIKH, Anuraag3 ; FENG, Xiao-Jiang4 ; MCARDLE, Jessica2 ; RABITZ, Herschel A4 ; SHENK, Thomas1 ; RABINOWITZ, Joshua D3
[1] Department of Molecular Biology, Lewis Thomas Laboratory, Princeton University, Princeton, New Jersey 08544, United States
[2] Department of Biochemistry and Biophysics, University of Rochester School of Medicine and Dentistry, 601 Elmwood Ave, Box 712, Rochester, New York 14642, United States
[3] Department of Chemistry and Lewis-Sigler Institute for Integrative Genomics, Carl Icahn Laboratory, Princeton University, Princeton, New Jersey 08544, United States
[4] Department of Chemistry, Frick Laboratory, Princeton University, Princeton, New Jersey 08544, United States - Source
Nature biotechnology (Print). 2008, Vol 26, Num 10, pp 1179-1186, 8 p ; ref : 58 ref
- CODEN
- NABIF9
- ISSN
- 1087-0156
- Scientific domain
- Biotechnology
- Publisher
- Nature Publishing Group, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Acide gras Antiviral Biosynthèse Cible Cytomegalovirus humain Inhibition Métabolisme Métabolome Réplication Thérapie Betaherpesvirinae Herpesviridae Virus
- Keyword (en)
- Fatty acids Antiviral Biosynthesis Target Human cytomegalovirus Inhibition Metabolism Metabolome Replication Therapy Betaherpesvirinae Herpesviridae Virus
- Keyword (es)
- Acido graso Antiviral Biosíntesis Blanco Human cytomegalovirus Inhibición Metabolismo Metaboloma Replicación Terapia Betaherpesvirinae Herpesviridae Virus
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A31 Biotechnology / 002A31D Industrial applications and implications. Economical aspects / 002A31D01 Health. Pharmaceutical industry / 002A31D01G Miscellaneous
- Discipline
- Biotechnology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20781980
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nbt.1500 
https://dx.doi.org/10.1038/nbt.1500
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