K-ras Mutations and Benefit from Cetuximab in Advanced Colorectal Cancer
- Author
- KARAPETIS, Christos S1 ; KHAMBATA-FORD, Shirin2 ; PRICE, Timothy J9 ; SHEPHERD, Lois4 ; AU, Heather-Jane10 ; LANGER, Christiane11 ; MOORE, Malcolm J12 ; ZALCBERG, John R13 ; JONKER, Derek J3 ; O'CALLAGHAN, Chris J4 ; DONGSHENG TU4 ; TEBBUTT, Niall C5 ; SIMES, R. John6 ; CHALCHAL, Haji7 ; SHAPIRO, Jeremy D8 ; ROBITAILLE, Sonia4
[1] Flinders Medical Centre and Flinders University, Adelaide, Australia
[2] Bristol-Myers Squibb Research and Development, Princeton, NJ, United States
[3] Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Canada
[4] National Cancer Institute of Canada Clinical Trials Group, Kingston, ON, Canada
[5] Austin Health, Melbourne, Australia
[6] National Health and Medical Research Council Clinical Trials Centre, University of Sydney, Sydney, Australia
[7] Allan Blair Cancer Centre, Regina, SK, Canada
[8] Cabrini Hospital and Alfred Hospital, Melbourne, Australia
[9] Queen Elizabeth Hospital and University of Adelaide, Adelaide, Australia
[10] Cross Cancer Institute, Edmonton, AB, Canada
[11] Bristol-Myers Squibb, Wallingford, CT, United States
[12] Princess Margaret Hospital, Toronto, Canada
[13] Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, Australia - Source
The New England journal of medicine. 2008, Vol 359, Num 17, pp 1757-1765, 9 p ; ref : 32 ref
- CODEN
- NEJMAG
- ISSN
- 0028-4793
- Scientific domain
- General medicine general surgery
- Publisher
- Massachusetts Medical Society, Boston, MA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Anticancéreux Cancer colorectal Cétuximab Gène K ras Gène onc cellulaire Gène onc Gène ras Immunomodulateur Mutation Médecine Protooncogène Stade avancé Anti-EGFR Anticorps monoclonal Cancer Pathologie de l'appareil digestif Pathologie de l'intestin Pathologie du côlon Pathologie du rectum Récepteur facteur croissance épiderme Tumeur maligne
- Keyword (en)
- Antineoplastic agent Colorectal cancer Cetuximab K ras Gene C-Onc gene Onc gene Ras gene Immunomodulator Mutation Medicine Protooncogene Advanced stage Monoclonal antibody Cancer Digestive diseases Intestinal disease Colonic disease Rectal disease Epidermal growth factor receptor Malignant tumor
- Keyword (es)
- Anticanceroso Cancer de colon y recto Cetuximab Gen K ras Gen onc celular Gen onc Gen ras Inmunomodulador Mutación Medicina Protooncogen Estadio avanzado Anticuerpo monoclonal Cáncer Aparato digestivo patología Intestino patología Colón patología Recto patología Receptor del factor de crecimiento epidérmico Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13B Stomach. Duodenum. Small intestine. Colon. Rectum. Anus / 002B13B01 Tumors
- Discipline
- Gastroenterology. Liver. Pancreas. Abdomen Generalities in medical sciences
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20811340
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1056/NEJMoa0804385 
https://dx.doi.org/10.1056/NEJMoa0804385
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