Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects
- Author
- ROSENBORG, Staffan Ohlsson1 ; MWINYI, Jessica2 ; ANDERSSON, Maria1 ; BALDWIN, R. Michael2 ; PEDERSEN, Rasmus Steen2 ; SIM, Sarah C2 ; BERTILSSON, Leif1 ; INGELMAN-SUNDBERG, Magnus2 ; ELIASSON, Erik1
[1] Karolinska Institutet, Department of Laboratory Medicine, Division of Clinical Pharmacology, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden
[2] Department of Physiology and Pharmacology, Section of Pharmacogenetics, Karolinska Institutet, Stockholm, Sweden - Source
European journal of clinical pharmacology. 2008, Vol 64, Num 12, pp 1175-1179, 5 p ; ref : 13 ref
- ISSN
- 0031-6970
- Scientific domain
- Pharmacology drugs
- Publisher
- Springer, Heidelberg
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Antidepressants Drug metabolism Pharmacogenetics Pharmacokinetics Poor responders Serotonin uptake inhibitor Therapeutic failure
- Keyword (fr)
- Allèle Antidépresseur Antisécrétoire Antiulcéreux Cinétique Cytochrome P450 Escitalopram Génétique Homme Individu sain Inhibiteur recapture Isozyme Médicament Métabolisme Oméprazole Pharmacocinétique Pharmacogénétique Psychotrope Sérotonine Traitement Dérivé du benzimidazole Enzyme H+/K+-exchanging ATPase Hydrolases Inhibiteur enzyme Inhibiteur pompe proton Inhibiteur sélectif recapture sérotonine Neurotransmetteur
- Keyword (en)
- Allele Antidepressant agent Antisecretory agent Antiulcer agent Kinetics Cytochrome P450 Escitalopram Genetics Human Healthy subject Reuptake inhibitor Isozyme Drug Metabolism Omeprazole Pharmacokinetics Pharmacogenetics Psychotropic Serotonin Treatment Benzimidazole derivatives Enzyme H+/K+-exchanging ATPase Hydrolases Enzyme inhibitor Proton pump inhibitor Selective serotonin reuptake inhibitor Neurotransmitter
- Keyword (es)
- Alelo Antidepresor Antisecretorio Antiulceroso Cinética Citocromo P450 Escitalopram Genética Hombre Individuo sano Inhibidor recaptura Isozima Medicamento Metabolismo Omeprazol Farmacocinética Farmacogenética Psicotropo Serotonina Tratamiento Benzimidazol derivado Enzima H+/K+-exchanging ATPase Hydrolases Inhibidor enzima Inhibidor bomba protón Inhibidor selectivo recaptura serotonin Neurotransmisor
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20896580
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
Access to the document
Install on your browser
DOI
10.1007/s00228-008-0529-z 
https://dx.doi.org/10.1007/s00228-008-0529-z
"O:13:\"PanistOpenUrl\":36:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000idc\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1007\/s00228-008-0529-z\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:96:\"Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects\";s:9:\"\u0000*\u0000jtitle\";s:41:\"European journal of clinical pharmacology\";s:9:\"\u0000*\u0000stitle\";s:23:\"Eur. j. clin. pharmacol\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:2:\"64\";s:8:\"\u0000*\u0000issue\";s:2:\"12\";s:8:\"\u0000*\u0000spage\";s:4:\"1175\";s:8:\"\u0000*\u0000epage\";s:4:\"1179\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0031-6970\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:9:\"ROSENBORG\";s:10:\"\u0000*\u0000aufirst\";s:15:\"Staffan Ohlsson\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:15:\"MWINYI, Jessica\";i:1;s:16:\"ANDERSSON, Maria\";i:2;s:19:\"BALDWIN, R. Michael\";i:3;s:22:\"PEDERSEN, Rasmus Steen\";i:4;s:12:\"SIM, Sarah C\";i:5;s:16:\"BERTILSSON, Leif\";i:6;s:25:\"INGELMAN-SUNDBERG, Magnus\";i:7;s:14:\"ELIASSON, Erik\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:96:\"Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects\";s:8:\"\u0000*\u0000place\";s:10:\"Heidelberg\";s:6:\"\u0000*\u0000pub\";s:8:\"Springer\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"5\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Panist access
"O:12:\"IstexOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1007\/s00228-008-0529-z\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:96:\"Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects\";s:9:\"\u0000*\u0000jtitle\";s:41:\"European journal of clinical pharmacology\";s:9:\"\u0000*\u0000stitle\";s:23:\"Eur. j. clin. pharmacol\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:2:\"64\";s:8:\"\u0000*\u0000issue\";s:2:\"12\";s:8:\"\u0000*\u0000spage\";s:4:\"1175\";s:8:\"\u0000*\u0000epage\";s:4:\"1179\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0031-6970\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:9:\"ROSENBORG\";s:10:\"\u0000*\u0000aufirst\";s:15:\"Staffan Ohlsson\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:15:\"MWINYI, Jessica\";i:1;s:16:\"ANDERSSON, Maria\";i:2;s:19:\"BALDWIN, R. Michael\";i:3;s:22:\"PEDERSEN, Rasmus Steen\";i:4;s:12:\"SIM, Sarah C\";i:5;s:16:\"BERTILSSON, Leif\";i:6;s:25:\"INGELMAN-SUNDBERG, Magnus\";i:7;s:14:\"ELIASSON, Erik\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:96:\"Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects\";s:8:\"\u0000*\u0000place\";s:10:\"Heidelberg\";s:6:\"\u0000*\u0000pub\";s:8:\"Springer\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"5\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Istex access
"O:16:\"UnpaywallOpenUrl\":35:{s:8:\"\u0000*\u0000email\";s:27:\"assistance-portail@inist.fr\";s:6:\"\u0000*\u0000fmt\";N;s:6:\"\u0000*\u0000doi\";s:25:\"10.1007\/s00228-008-0529-z\";s:6:\"\u0000*\u0000pii\";N;s:7:\"\u0000*\u0000pmid\";N;s:9:\"\u0000*\u0000atitle\";N;s:9:\"\u0000*\u0000jtitle\";N;s:9:\"\u0000*\u0000stitle\";N;s:7:\"\u0000*\u0000date\";N;s:9:\"\u0000*\u0000volume\";N;s:8:\"\u0000*\u0000issue\";N;s:8:\"\u0000*\u0000spage\";N;s:8:\"\u0000*\u0000epage\";N;s:8:\"\u0000*\u0000pages\";N;s:7:\"\u0000*\u0000issn\";N;s:8:\"\u0000*\u0000eissn\";N;s:9:\"\u0000*\u0000aulast\";N;s:10:\"\u0000*\u0000aufirst\";N;s:9:\"\u0000*\u0000auinit\";N;s:10:\"\u0000*\u0000auinitm\";N;s:5:\"\u0000*\u0000au\";N;s:9:\"\u0000*\u0000aucorp\";N;s:7:\"\u0000*\u0000isbn\";N;s:8:\"\u0000*\u0000coden\";N;s:8:\"\u0000*\u0000genre\";N;s:7:\"\u0000*\u0000part\";N;s:9:\"\u0000*\u0000btitle\";N;s:8:\"\u0000*\u0000title\";N;s:8:\"\u0000*\u0000place\";N;s:6:\"\u0000*\u0000pub\";N;s:10:\"\u0000*\u0000edition\";N;s:9:\"\u0000*\u0000tpages\";N;s:9:\"\u0000*\u0000series\";N;s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";N;}"
Unpaywall access
"O:16:\"EuropePMCOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1007\/s00228-008-0529-z\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:96:\"Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects\";s:9:\"\u0000*\u0000jtitle\";s:41:\"European journal of clinical pharmacology\";s:9:\"\u0000*\u0000stitle\";s:23:\"Eur. j. clin. pharmacol\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:2:\"64\";s:8:\"\u0000*\u0000issue\";s:2:\"12\";s:8:\"\u0000*\u0000spage\";s:4:\"1175\";s:8:\"\u0000*\u0000epage\";s:4:\"1179\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0031-6970\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:9:\"ROSENBORG\";s:10:\"\u0000*\u0000aufirst\";s:15:\"Staffan Ohlsson\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:15:\"MWINYI, Jessica\";i:1;s:16:\"ANDERSSON, Maria\";i:2;s:19:\"BALDWIN, R. Michael\";i:3;s:22:\"PEDERSEN, Rasmus Steen\";i:4;s:12:\"SIM, Sarah C\";i:5;s:16:\"BERTILSSON, Leif\";i:6;s:25:\"INGELMAN-SUNDBERG, Magnus\";i:7;s:14:\"ELIASSON, Erik\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:96:\"Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects\";s:8:\"\u0000*\u0000place\";s:10:\"Heidelberg\";s:6:\"\u0000*\u0000pub\";s:8:\"Springer\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"5\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Europe PubMed Central access
"O:11:\"BaseOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1007\/s00228-008-0529-z\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:96:\"Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects\";s:9:\"\u0000*\u0000jtitle\";s:41:\"European journal of clinical pharmacology\";s:9:\"\u0000*\u0000stitle\";s:23:\"Eur. j. clin. pharmacol\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:2:\"64\";s:8:\"\u0000*\u0000issue\";s:2:\"12\";s:8:\"\u0000*\u0000spage\";s:4:\"1175\";s:8:\"\u0000*\u0000epage\";s:4:\"1179\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0031-6970\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:9:\"ROSENBORG\";s:10:\"\u0000*\u0000aufirst\";s:15:\"Staffan Ohlsson\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:15:\"MWINYI, Jessica\";i:1;s:16:\"ANDERSSON, Maria\";i:2;s:19:\"BALDWIN, R. Michael\";i:3;s:22:\"PEDERSEN, Rasmus Steen\";i:4;s:12:\"SIM, Sarah C\";i:5;s:16:\"BERTILSSON, Leif\";i:6;s:25:\"INGELMAN-SUNDBERG, Magnus\";i:7;s:14:\"ELIASSON, Erik\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:96:\"Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects\";s:8:\"\u0000*\u0000place\";s:10:\"Heidelberg\";s:6:\"\u0000*\u0000pub\";s:8:\"Springer\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"5\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Base Search access
"O:12:\"ArXivOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:25:\"10.1007\/s00228-008-0529-z\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:96:\"Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects\";s:9:\"\u0000*\u0000jtitle\";s:41:\"European journal of clinical pharmacology\";s:9:\"\u0000*\u0000stitle\";s:23:\"Eur. j. clin. pharmacol\";s:7:\"\u0000*\u0000date\";s:4:\"2008\";s:9:\"\u0000*\u0000volume\";s:2:\"64\";s:8:\"\u0000*\u0000issue\";s:2:\"12\";s:8:\"\u0000*\u0000spage\";s:4:\"1175\";s:8:\"\u0000*\u0000epage\";s:4:\"1179\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0031-6970\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:9:\"ROSENBORG\";s:10:\"\u0000*\u0000aufirst\";s:15:\"Staffan Ohlsson\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:8:{i:0;s:15:\"MWINYI, Jessica\";i:1;s:16:\"ANDERSSON, Maria\";i:2;s:19:\"BALDWIN, R. Michael\";i:3;s:22:\"PEDERSEN, Rasmus Steen\";i:4;s:12:\"SIM, Sarah C\";i:5;s:16:\"BERTILSSON, Leif\";i:6;s:25:\"INGELMAN-SUNDBERG, Magnus\";i:7;s:14:\"ELIASSON, Erik\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:0:\"\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:96:\"Kinetics of omeprazole and escitalopram in relation to the CYP2C19*17 allele in healthy subjects\";s:8:\"\u0000*\u0000place\";s:10:\"Heidelberg\";s:6:\"\u0000*\u0000pub\";s:8:\"Springer\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:1:\"5\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
arXiv access
