Preventive but Not Late Amiloride Therapy Reduces Morbidity and Mortality of Lung Disease in βENaC-overexpressing Mice
- Author
- ZHE ZHOU1 ; TREIS, Diana1 ; SCHUBERT, Susanne C1 ; HARM, Maria1 ; SCHATTERNY, Jolanthe1 ; HIRTZ, Stephanie1 ; DUERR, Julia1 ; BOUCHER, Richard C2 ; MALL, Marcus A1
[1] Pediatric Pulmonology and Cystic Fibrosis Center, Department of Pediatrics III, University of Heidelberg, Heidelberg, Germany
[2] Cystic Fibrosis/Pulmonary Research and Treatment Center, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States - Source
American journal of respiratory and critical care medicine. 2008, Vol 178, Num 12, pp 1245-1256, 12 p ; ref : 69 ref
- ISSN
- 1073-449X
- Scientific domain
- Pneumology
- Publisher
- American Thoracic Society, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- airway surface liquid cystic fibrosis epithelial Na+ channels mucus pharmacotherapy
- Keyword (fr)
- Amiloride Animal Diurétique épargnant K Epithélium Morbidité Mortalité Mucoviscidose Mucus Pathologie des poumons Prévention Réanimation Soin intensif Souris Traitement Enzyme Hydrolases Inhibiteur enzyme Maladie héréditaire Maladie métabolique Mammalia Pathologie de l'appareil digestif Pathologie de l'appareil respiratoire Pathologie du pancréas Peptidases Rodentia Serine endopeptidases Vertebrata u-Plasminogen activator
- Keyword (en)
- Amiloride Animal Potassium sparing diuretic Epithelium Morbidity Mortality Cystic fibrosis Mucus Lung disease Prevention Resuscitation Intensive care Mouse Treatment Enzyme Hydrolases Enzyme inhibitor Genetic disease Metabolic diseases Mammalia Digestive diseases Respiratory disease Pancreatic disease Peptidases Rodentia Serine endopeptidases Vertebrata u-Plasminogen activator
- Keyword (es)
- Amilorida Animal Diurético ahorrador potasio Epitelio Morbilidad Mortalidad Mucoviscidosis Moco Pulmón patología Prevención Reanimación Cuidado intensivo Ratón Tratamiento Enzima Hydrolases Inhibidor enzima Enfermedad hereditaria Metabolismo patología Mammalia Aparato digestivo patología Aparato respiratorio patología Páncreas patología Peptidases Rodentia Serine endopeptidases Vertebrata u-Plasminogen activator
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B26 Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) / 002B26D Diseases of the respiratory system
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B27 Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy / 002B27B Intensive care medicine
- Discipline
- Anaesthesia. Reanimation. Transfusion. Cell therapy and gene therapy Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, speech therapy, crenotherapy. Dietary management and various treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 20971084
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1164/rccm.200803-442OC 
https://dx.doi.org/10.1164/rccm.200803-442OC
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