Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice
- Author
- JING XU1 ; LLOYD, David J1 ; CHEN, Jin-Long1 ; DAE YOUNG JUNG4 ; ZHIYOU ZHANG4 ; HWI JIN KO4 ; KIM, Jason K4 ; VENIANT, Murielle M1 ; HALE, Clarence1 ; STANISLAUS, Shanaka1 ; CHEN, Michelle1 ; SIVITS, Glenn1 ; VONDERFECHT, Steven2 ; HECHT, Randy3 ; LI, Yue-Sheng3 ; LINDBERG, Richard A1
[1] Department of Metabolic Disorders, Amgen, Thousand Oaks, California, United States
[2] Department of Pathology, Amgen, Thousand Oaks, California, United States
[3] Department of Protein Sciences, Amgen, Thousand Oaks, California, United States
[4] Department of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States - Source
Diabetes (New York, NY). 2009, Vol 58, Num 1, pp 250-259, 10 p ; ref : 32 ref
- CODEN
- DIAEAZ
- ISSN
- 0012-1797
- Scientific domain
- Endocrinology; Nutrition, obesity, metabolic disorders
- Publisher
- American Diabetes Association, Alexandria, VA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Diabète Etat nutritionnel Facteur croissance fibroblaste Insuline Obésité Régime alimentaire Sensibilité Souris Stéatose hépatique Alimentation Endocrinopathie Hormone pancréatique Mammalia Pathologie de l'appareil digestif Pathologie du foie Rodentia Trouble de la nutrition Vertebrata
- Keyword (en)
- Animal Diabetes mellitus Nutritional status Fibroblast growth factor Insulin Obesity Diet Sensitivity Mouse Fatty liver Feeding Endocrinopathy Pancreatic hormone Mammalia Digestive diseases Hepatic disease Rodentia Nutrition disorder Vertebrata
- Keyword (es)
- Animal Diabetes Estado nutricional Factor crecimiento fibroblasto Insulina Obesidad Régimen alimentario Sensibilidad Ratón Hígado graso Alimentación Endocrinopatía Hormona pancreática Mammalia Aparato digestivo patología Hígado patología Rodentia Trastorno nutricíon Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13C Liver. Biliary tract. Portal circulation. Exocrine pancreas / 002B13C03 Other diseases. Semiology
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21E Endocrine pancreas. Apud cells (diseases) / 002B21E01 Diabetes. Impaired glucose tolerance / 002B21E01A Etiopathogenesis. Screening. Investigations. Target tissue resistance
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B22 Metabolic diseases / 002B22B Obesity
- Discipline
- Endocrinopathies Gastroenterology. Liver. Pancreas. Abdomen Metabolic diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 21020996
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.2337/db08-0392 
https://dx.doi.org/10.2337/db08-0392
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