Crypt stem cells as the cells-of-origin of intestinal cancer
- Author
- BARKER, Nick1 2 ; RIDGWAY, Rachel A3 ; VAN ES, Johan H1 2 ; VAN DE WETERING, Marc1 2 ; BEGTHEL, Harry1 2 ; VAN DEN BORN, Maaike1 2 ; DANENBERG, Esther1 2 ; CLARKE, Alan R4 ; SANSOM, Owen J3 ; CLEVERS, Hans1 2
[1] Hubrecht Institute for Developmental Biology and Stem Cell Research, Uppsalalaan 8, 3584CT Utrecht, Netherlands
[2] University Medical Centre Utrecht, Netherlands
[3] Beatson Institute for Cancer Research, Glasgow G611BD, United Kingdom
[4] cardiff School of Biosciences, Cardiff CF10 3US, United Kingdom - Source
Nature (London). 2009, Vol 457, Num 7229, pp 608-611, 4 p ; ref : 30 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Cancer de l'intestin Cancérologie Carcinogenèse Cellule souche Glande Lieberkuhn Gène suppresseur tumeur Origine cellule Souris Transformation maligne Gène APC Cancer Génétique Mammalia Pathologie de l'appareil digestif Pathologie de l'intestin Rodentia Tumeur maligne Vertebrata
- Keyword (en)
- Animal Intestinal cancer Cancerology Carcinogenesis Stem cell Lieberkuhn gland Tumor suppressor gene Cell origin Mouse Malignant transformation APC Gene Cancer Genetics Mammalia Digestive diseases Intestinal disease Rodentia Malignant tumor Vertebrata
- Keyword (es)
- Animal Cáncer del intestino Cancerología Carcinogénesis Célula primitiva Glándula Lieberkuhn Gen supresor tumor Origen celular Ratón Transformación maligna Gen APC Cáncer Genética Mammalia Aparato digestivo patología Intestino patología Rodentia Tumor maligno Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04D Animal tumors. Experimental tumors / 002B04D07 Experimental digestive system and abdominal tumors
- Discipline
- Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 21030270
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature07602 
https://dx.doi.org/10.1038/nature07602
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