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The Karyopherin proteins, Crm1 and Karyopherin β1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation

Author
VAN DER WATT, Pauline J1 ; MASKE, Christopher P2 ; HENDRICKS, Denver T1 ; IQBAL PARKER, M1 3 ; DENNY, Lynette4 ; GOVENDER, Dhirendra2 ; BIRRER, Michael J5 ; LEANER, Virna D1
[1] Division of Medical Biochemistry, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, South Africa
[2] Division of Anatomical Pathology, Faculty of Health Sciences, University of Cape Town, South Africa
[3] International Center of Genetic Engineering and Biotechnology (ICGEB), Cape Town, (ICGEB) Cape Town Component, South Africa
[4] Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of Cape Town, South Africa
[5] Department of Cell and Cancer Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States
Source

International journal of cancer (Print). = Journal international du cancer. 2009, Vol 124, Num 8, pp 1829-1840, 12 p ; ref : 47 ref

CODEN
IJCNAW
ISSN
0020-7136
Scientific domain
Medical oncology
Publisher
Wiley-Blackwell, Hoboken, NJ
Publication country
United States
Document type
Article
Language
English
Author keyword
Crm1 Karyopherin α2 Karyopherin β1 cervical cancer nuclear transport proteins
Keyword (fr)
Cancer du col de l'utérus Cancérologie Cellule tumorale Multiplication cellulaire Protéine nucléaire Protéine transport Surexpression génique Karyopherine alpha 2 Survie cellulaire Cancer Pathologie de l'appareil génital femelle Pathologie du col de l'utérus Tumeur maligne
Keyword (en)
Cervical cancer Cancerology Tumor cell Cell proliferation Nuclear protein Carrier protein Gene overexpression Karyopherin alpha 2 Cell survival Cancer Female genital diseases Uterine cervix diseases Malignant tumor
Keyword (es)
Cáncer de cuello del útero Cancerología Célula tumoral Multiplicación celular Proteína nuclearia Proteína transportador Sobreexpresión genética Supervivencia celular Cáncer Aparato genital hembra patología Cuello útero patología Tumor maligno
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B20 Gynecology. Andrology. Obstetrics / 002B20C Female genital diseases / 002B20C02 Tumors

Discipline
Gynecology. Andrology. Obstetrics Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
21207151

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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