Inhibition of JAK2 protects renal endothelial and epithelial cells from oxidative stress and cyclosporin A toxicity
- Author
- NERIA, Fernando1 2 ; CASTILLA, Maria A1 ; FERNANDEZ SANCHEZ, Ruth1 2 ; GONZALEZ PACHECO, Francisco R1 ; DEUDERO, Juan J. P1 2 ; CALABIA, Olalla1 2 ; TEJEDOR, Alberto3 ; MANZARBEITIA, Felix1 ; ORTIZ, Alberto1 2 ; CARAMELO, Carlos1 2
[1] Laboratorio de Nefrologia-Hipertension, Fundacion Jimenez Diaz-Capio, Universidad Autonoma, Madrid, Spain
[2] Ιnstituto de Investigación Renal Reina Sofiá, Madrid, Spain
[3] Laboratorio de Fisiopatologia Renal, Hospital General Universitario Gregorio Marañon, Madrid, Spain - Source
Kidney international. 2009, Vol 75, Num 2, pp 227-234, 8 p ; ref : 46 ref
- CODEN
- KDYIA5
- ISSN
- 0085-2538
- Scientific domain
- Urology, nephrology
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- acute kidney injury cyclosporine nephrotoxicity endothelial cells transplantation tubular epithelium
- Keyword (fr)
- Cellule endothéliale Cellule épithéliale Ciclosporine Epithélium Immunodépresseur Inhibition Lésion rénale aiguë Néphrologie Néphrotoxicité Protein-tyrosine kinase Rein Stress oxydatif Toxicité Traitement Transplantation Tubule rénal Urologie JAK2 protein tyrosine kinase Appareil urinaire Chirurgie Enzyme Greffe Inhibiteur de la calcineurine Pathologie de l'appareil urinaire Pathologie du rein Transferases
- Keyword (en)
- Endothelial cell Epithelial cell Ciclosporin Epithelium Immunosuppressive agent Inhibition Acute kidney injury Nephrology Nephrotoxicity Protein-tyrosine kinase Kidney Oxidative stress Toxicity Treatment Transplantation Renal tubule Urology JAK2 protein tyrosine kinase Urinary system Surgery Enzyme Graft Calcineurin inhibitor Urinary system disease Kidney disease Transferases
- Keyword (es)
- Célula endotelial Célula epitelial Ciclosporina Epitelio Inmunodepresor Inhibición Lesión renal aguda Nefrología Nefrotoxicidad Protein-tyrosine kinase Riñón Estrés oxidativo Toxicidad Tratamiento Trasplantación Túbulo renal Urología JAK2 protein tyrosine kinase Aparato urinario Cirugía Enzima Injerto Inhibidor calcineurina Aparato urinario patología Riñón patología Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B14 Nephrology. Urinary tract diseases / 002B14E Urinary system involvement in other diseases. Miscellaneous / 002B14E01 Kidneys
- Discipline
- Nephrology. Urinary tract diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 21217996
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/ki.2008.487 
https://dx.doi.org/10.1038/ki.2008.487
