Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect
- Author
- LARA, E1 ; MAI, A2 ; MONTOYA, G5 ; OYARZABAL, J6 ; VELASCO, S7 ; SERRANO, M7 ; WITT, M8 ; VILLAR-GAREA, A9 ; INHOF, A9 ; MATO, J. M4 ; ESTELLER, M10 ; FRAGA, M. F1 11 ; CALVANESE, V1 ; ALTUCCI, L3 ; LOPEZ-NIEVA, P1 ; MARTINEZ-CHANTAR, M. L4 ; VARELA-REY, M4 ; ROTILI, D2 ; NEBBIOSO, A3 ; ROPERO, S1
[1] Cancer Epigenetics Laboratory, Spanish National Cancer Research Centre (CNIO), Madrid, Spain
[2] Dipartimento di Studi Farmaceutici, Istituto Pasteur, Fondazione Cenci Bolognetti, Università degli Studi di Roma 'La Sapienza', Roma, Italy
[3] Dipartimento di Patologia Generale, Seconda Universitd degli Studi di Napoli, Napoli, Italy
[4] CIC bioGUNE, CIBERehd, Bizkaia Technology Park, Bizkaia, Spain
[5] Macromolecular Crystallography Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain
[6] Computational Chemistry Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain
[7] Tumour Suppression Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain
[8] Bruker Daltonik GmbH, Bremen, Germany
[9] Histone Modifications Group, Adolf-Butenandt Institut, University of Munich, Munich, Germany
[10] Cancer Epigenetics and Biology Program (PEBC), Catalan Institute of Oncology (ICO), Barcelona, Spain
[11] Department of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Cantoblanco, Madrid, Spain - Source
Oncogene (Basingstoke). 2009, Vol 28, Num 6, pp 781-791, 11 p ; ref : 1 p
- ISSN
- 0950-9232
- Scientific domain
- Cell biology, histology; Medical oncology; Genetics
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- HDACs inhibitors Sirtuins apoptosis cancer
- Keyword (fr)
- Apoptose Carcinogenèse Inhibiteur Tumeur maligne Histone deacetylase Cancer
- Keyword (en)
- Apoptosis Carcinogenesis Inhibitor Malignant tumor Histone deacetylase Cancer
- Keyword (es)
- Apoptosis Carcinogénesis Inhibidor Tumor maligno Histone deacetylase Cáncer
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H04 Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H05 Ageing, cell death
- Discipline
- Molecular and cell biology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 21236241
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/onc.2008.436 
https://dx.doi.org/10.1038/onc.2008.436
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