Polysaccharide nanogel delivery of a TNF-α and RANKL antagonist peptide allows systemic prevention of bone loss
- Author
- ALLES, Neil1 2 ; SOYSA, Niroshani S1 ; HUSSAIN, Anower1 ; TOMOMATSU, Nobuyoshi1 ; SAITO, Hiroaki3 ; BARON, Roland3 ; MORIMOTO, Nobuyuki4 ; AOKI, Kazuhiro1 ; AKIYOSHI, Kazunari2 4 ; OHYA, Keiichi1
[1] Section of Pharmacology, Department of Hard Tissue Engineering, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8549, Japan
[2] Global Center of Excellence (G-COE) Program, Tokyo Medical and Dental University, Japan
[3] Harvard School of Dental Medicine and Harvard Medical School, Boston, MA 02115, United States
[4] Organic Biomaterials, Institute of Biomaterials and Bioengineering, Graduate School, Tokyo Medical & Dental University, Tokyo, Japan - Source
European journal of pharmaceutical sciences. 2009, Vol 37, Num 2, pp 83-88, 6 p ; ref : 1/2 p
- ISSN
- 0928-0987
- Scientific domain
- Pharmacology drugs
- Publisher
- Elsevier, Kindlington
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Aggregation Cholesterol-bearing pullulan Drug delivery system Nanogel Peptide drugs Stability
- Keyword (fr)
- Agrégation Antagoniste Cholestérol Facteur nécrose tumorale α Modalité traitement Médicament Nanogel Ostéopénie Peptide Perte de substance osseuse Polyoside Prévention Stabilité Technologie pharmaceutique Vecteur médicament Voie administration Pullulane Cytokine Pathologie du système ostéoarticulaire Propriété physicochimique
- Keyword (en)
- Aggregation Antagonist Cholesterol Tumor necrosis factor α Application method Drug Nanogel Osteopenia Peptides Bone defect Polysaccharide Prevention Stability Pharmaceutical technology Drug carrier Route of administration Pullulan Cytokine Diseases of the osteoarticular system Physicochemical properties
- Keyword (es)
- Agregación Antagonista Colesterol Factor necrosis tumoral α Modalidad tratamiento Medicamento Nanogel Osteopenia Péptido Pérdida substancia hueso Poliósido Prevención Estabilidad Tecnología farmacéutica Vector medicamento Vía administración Citoquina Sistema osteoarticular patología Propiedad fisicoquímica
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 21386574
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.ejps.2009.01.002 
https://dx.doi.org/10.1016/j.ejps.2009.01.002
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