Common genetic variants on 5p14.1 associate with autism spectrum disorders
- Author
- KAI WANG1 ; HAITAO ZHANG1 ; KIM, Cecilia E1 ; CUIPING HOU1 ; FRACKELTON, Edward1 ; CHIAVACCI, Rosetta1 ; TAKAHASHI, Nagahide5 ; SAKURAI, Takeshi5 ; RAPPAPORT, Eric6 ; LAJONCHERE, Clara M7 ; MUNSON, Jeffrey8 ; ESTES, Annette8 ; DEQIONG MA2 ; KORVATSKA, Olena8 ; PIVEN, Joseph9 ; SONNENBLICK, Lisa I4 ; ALVAREZ RETUERTO, Ana I4 ; HERMAN, Edward I4 ; HONGMEI DONG4 ; HUTMAN, Ted4 ; SIGMAN, Marian4 ; OZONOFF, Sally10 ; KLIN, Ami11 ; BUCAN, Maja3 ; OWLEY, Thomas12 ; SWEENEY, John A12 ; BRUNE, Camille W12 ; CANTOR, Rita M13 ; BERNIER, Raphael8 ; GILBERT, John R2 ; CUCCARO, Michael L2 ; MCMAHON, William M14 ; MILLER, Judith14 ; STATE, Matthew W11 ; GLESSNER, Joseph T1 ; WASSINK, Thomas H15 ; COON, Hilary14 ; LEVY, Susan E6 ; SCHULTZ, Robert T6 ; NURNBERGER, John I16 ; HAINES, Jonathan L17 ; SUTCLIFFE, James S18 ; COOK, Edwin H12 ; MINSHEW, Nancy J19 ; BUXBAUM, Joseph D20 5 ; ABRAHAMS, Brett S4 ; DAWSON, Geraldine8 ; GRANE, Struan F. A1 6 ; GESCHWIND, Daniel H4 ; PERICAK-VANCE, Margaret A2 ; SCHELLENBERG, Gerard D21 ; HAKONARSON, Hakon1 6 ; SALYAKINA, Daria2 ; IMIELINSKI, Marcin1 ; BRADFIELD, Jonathan P1 ; SLEIMAN, Patrick M. A1
[1] Center for Applied Genomics, Children's Hospital of Philadelphia, Pennsylvania 19104, United States
[2] The Miami Institute for Human Genomics and Department of Human Genetics, University of Miami, Miami, Florida 33101, United States
[3] Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania 19014, United States
[4] Department of Neurology and Center for Autism Research and Treatment, University of California Los Angeles, Los Angeles, California 90095, United States
[5] Seaver Autism Center for Research and Treatment, Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029, United States
[6] Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19014, United States
[7] Department of Biomedical Engineering, University of Southern California and Autism Speaks, Los Angeles, California 90089, United States
[8] Department of Psychiatry, University of Washington, Seattle, Washington 98105, United States
[9] Department of Psychiatry, University of North Carolina and Carolina Institute for Developmental Disabilities, Chapel Hill, North Carolina 27599, United States
[10] The M,I.N.D. Institute and Department of Psychiatry and Behavioral Sciences, University of California Davis, Sacramento, California 95817, United States
[11] Department of Genetics and Child Study Center, Yale University, New Haven, Connecticut 06520, United States
[12] Institute for Juvenile Research and Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois 60608, United States
[13] Department of Human Genetics, University of California Los Angeles, Los Angeles, California 90095, United States
[14] Department of Psychiatry, University of Utah, Salt Lake City, Utah 84132, United States
[15] Department of Psychiatry, University of lowa, Iowa City, Iowa 84112, United States
[16] Institute of Psychiatric Research, Indiana University, Indianapolis, Indiana 46202, United States
[17] Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee 37232, United States
[18] Center for Molecular Neuroscience and Vanderbilt Kennedy Center, Vanderbilt University, Nashville, Tennessee 37232, United States
[19] Departments of Psychiatry and Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States
[20] Departments of Psychiatry, Neuroscience, and Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York 10029, United States
[21] Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19014, United States - Source
Nature (London). 2009, Vol 459, Num 7246, pp 528-533, 6 p ; ref : 51 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Autisme Cadhérine Codage Environnement social Etude cohorte Etude familiale Homme Polymorphisme mononucléotide Protéine CAM Santé mentale Santé publique Trouble envahissant du développement Variant génétique Gène CDH10 Gène CDH9 Etats-Unis Déterminisme génétique Génétique Trouble du développement Amérique du Nord Amérique
- Keyword (en)
- Autism Cadherin Coding Social environment Cohort study Family study Human Single nucleotide polymorphism Cell adhesion molecule Mental health Public health Pervasive developmental disorder Genetic variant United States Genetic determinism Genetics Developmental disorder North America America
- Keyword (es)
- Autismo Cadherina Codificación Contexto social Estudio cohorte Estudio familiar Hombre Polimorfismo mononucleótido Proteína CAM Salud mental Salud pública Disturbio invasor del desarrollo Variante genética Estados Unidos Determinismo genético Genética Trastorno desarrollo America del norte America
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B18 Psychopathology. Psychiatry / 002B18D Child clinical studies / 002B18D04 Developmental disorders / 002B18D04B Infantile autism
- Francis
- 770 Psychology. Psychoanalysis. Psychiatry / 770-D Psychopathology. Psychiatry / 770-D04 Child clinical studies / 770-D04D Developmental disorders / 770-D04D02 Infantile autism
- Discipline
- Psychopathology. Psychiatry. Clinical psychology
- Origin
- Inist-CNRS
- Database
- FRANCIS ; PASCAL
- INIST identifier
- 21471837
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature07999 
https://dx.doi.org/10.1038/nature07999
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arXiv access
