Polycyclic cage structures as carrier molecules for neuroprotective non-steroidal anti-inflammatory drugs
- Author
- PRINS, Louis H. A1 ; DU FREEZ, Jan L2 ; VAN DYK, Sandra1 ; MALAN, Sarel F1
[1] Pharmaceutical Chemistry, School of Pharmacy, North-West University, Potchefstroom 2520, South Africa
[2] Central Analytical Lahoratory. School of Pharmacy, North-West University, Potchefstroom, 2520, South Africa - Source
European journal of medicinal chemistry. 2009, Vol 44, Num 6, pp 2577-2582, 6 p ; ref : 26 ref
- CODEN
- EJMCA5
- ISSN
- 0223-5234
- Scientific domain
- Organic chemistry; Pharmacology drugs
- Publisher
- Elsevier, Kidlington
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Amantadine Antioxidant activity Blood-brain barrier permeability Non-steroidal anti-inflammatory drugs (NSAIDs) Polycyclic cage Prodrugs
- Keyword (fr)
- Acide acétylsalicylique Activité biologique Animal Antiinflammatoire non stéroïde Antioxydant Barrière hématoencéphalique Composé cage Composé polycyclique Distribution Dérivé de l'amantadine Encéphale Hétérocycle oxygène azote Ibuprofène In vitro In vivo Neuroprotecteur Perméabilité cellulaire Promédicament Souris Synthèse chimique Système nerveux central Tissu Voie intrapéritonéale Azaoxaheptacyclotétradécane dérivé Biodistribution Dérivé de l'acide arylpropionique Mammalia Rodentia Salicylés Vertebrata
- Keyword (en)
- Acetylsalicylic acid Biological activity Animal Non steroidal antiinflammatory agent Antioxidant Blood brain barrier Cage compound Polycyclic compound Distribution Amantadine derivatives Encephalon Oxygen nitrogen heterocycle Ibuprofen In vitro In vivo Neuroprotective agent Cell permeability Prodrug Mouse Chemical synthesis Central nervous system Tissue Intraperitoneal administration Arylpropionic acid derivatives Mammalia Rodentia Salicylates Vertebrata
- Keyword (es)
- Acetilsalicilico ácido Actividad biológica Animal Antiinflamatorio no esteroide Antioxidante Barrera hematoencefálica Compuesto jaula Compuesto policíclico Distribución Amantadina derivada Encéfalo Heterociclo oxígeno nitrógeno Ibuprofeno In vitro In vivo Neuroprotector Permeabilidad celular Promedicamento Ratón Síntesis química Sistema nervioso central Tejido Vía intraperitoneal Arilpropionico ácido derivado Mammalia Rodentia Salicilatos Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02N General and cellular metabolism. Vitamins
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 21487750
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.ejmech.2009.01.030 
https://dx.doi.org/10.1016/j.ejmech.2009.01.030
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