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Synergistic drug combinations tend to improve therapeutically relevant selectivity

Author
LEHAR, Joseph1 2 ; KRUEGER, Andrew S2 ; LEE, Margaret S1 ; ZIMMERMANN, Grant R1 ; BORISY, Alexis A1 ; AVERY, William1 ; HEILBUT, Adrian M1 ; JOHANSEN, Lisa M1 ; ROYDON PRICE, E1 ; RICKLES, Richard J1 ; SHORT, Glenn F1 ; STAUNTON, Jane E1 ; XIAOWEI JIN1
[1] CombinatoRx Inc., Cambridge, Massachusetts, United States
[2] Boston University Bioinformatics/Bioengineering, Boston, Massachusetts, United States
Source

Nature biotechnology (Print). 2009, Vol 27, Num 7, pp 659-666, 8 p ; ref : 47 ref

CODEN
NABIF9
ISSN
1087-0156
Scientific domain
Biotechnology
Publisher
Nature Publishing Group, New York, NY
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Médicament Optimisation Synergie Sélectivité
Keyword (en)
Drug Optimization Synergism Selectivity
Keyword (es)
Medicamento Optimización Sinergia Selectividad
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A31 Biotechnology

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A07 Miscellaneous

Discipline
Biotechnology General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
21714797

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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