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Synthesis and cytotoxic activity of α-santonin derivatives

Author
ARANTES, Francisco F. P1 ; BARBOSA, Luiz C. A1 ; ALVARENGA, Elson S1 ; DEMUNER, Antônio J1 ; BEZERRA, Daniel P2 ; FERREIRA, José R. O2 ; COSTA-LOTUFO, Leticia V2 ; PESSOA, Claudia2 ; MORAES, Manoel O2
[1] Department of Chemistry, Federal University of Viçosa, Av. P.H. Rolfs, S/N, CEP 36570-000 Viçosa, MG, Brazil
[2] Department of Physiology and Pharmacology, Federal University of Ceará, Rua Coronel Nunes de Melo 1127, CEP 60431-970 Fortaleza, CE, Brazil
Source

European journal of medicinal chemistry. 2009, Vol 44, Num 9, pp 3739-3745, 7 p ; ref : 36 ref

CODEN
EJMCA5
ISSN
0223-5234
Scientific domain
Organic chemistry; Pharmacology drugs
Publisher
Elsevier, Kidlington
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Cytotoxicity Photochemistry Sesquiterpene lactones α-Santonin derivatives
Keyword (fr)
Activité biologique Anticancéreux Cellule tumorale Cytotoxicité Homme In vitro Lactone Lignée cellulaire Réaction photochimique Santonine Sesquiterpène Synthèse chimique Terpénoïde Cyclopenta[2,3]cyclopropa[1,2-g]benzofurane dérivé Cyclopentacyclopropabenzofurane Eudesmane dérivé Eudesmanolide Guaïane dérivé Guaïanolide Lumisantonine
Keyword (en)
Biological activity Antineoplastic agent Tumor cell Cytotoxicity Human In vitro Lactone Cell line Photochemical reaction Sesquiterpenes Chemical synthesis Terpenoid
Keyword (es)
Actividad biológica Anticanceroso Célula tumoral Citotoxicidad Hombre In vitro Lactona Línea celular Reacción fotoquímica Sesquiterpeno Síntesis química Terpenoide
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
21777583

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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