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Human CD80/IL2 lentivirus transduced acute myeloid leukaemia cells enhance cytolytic activity in vitro in spite of an increase in regulatory CD4+ T cells in a subset of cultures

Author
INGRAM, Wendy1 ; KORDASTI, Shahram1 ; CHAN, Lucas1 ; BARBER, Linda D1 ; TYE, Gee J1 ; HARDWICK, Nicola1 ; MUFTI, Ghulam J1 ; FARZANEH, Farzin1
[1] Department of Haematological Medicine, King's College London, Rayne Institute, 123 Coldharbour Lane, London SE5 9NU, United Kingdom
Source

Cancer immunology and immunotherapy. 2009, Vol 58, Num 10, pp 1679-1690, 12 p ; ref : 57 ref

CODEN
CIIMDN
ISSN
0340-7004
Scientific domain
Biochemistry, molecular biology, biophysics; Medical oncology; Immunology, immunopathology, allergology
Publisher
Springer, Heidelberg
Publication country
Germany
Document type
Article
Language
English
Author keyword
Acute myeloid leukemia CD80 IL2 Lentivirus Regulatory T cells
Keyword (fr)
Cytolyse Homme Immunothérapie In vitro Interleukine 2 Lentivirus Leucémie aiguë myéloblastique Lymphocyte T CD4 Lymphocyte T Molécule costimulation Traitement Transduction signal Antigène CD80 Cellule régulatrice Molécule B7-1 Cancer Cytokine Hémopathie maligne Retroviridae Virus
Keyword (en)
Cytolysis Human Immunotherapy In vitro Interleukin 2 Lentivirus Acute myelogenous leukemia CD4 T lymphocyte T-Lymphocyte Costimulatory molecule Treatment Signal transduction Regulatory cell B7-1 Molecule Cancer Cytokine Malignant hemopathy Retroviridae Virus
Keyword (es)
Citólisis Hombre Inmunoterapia In vitro Interleuquina 2 Lentivirus Leucemia aguda mieloblástica Linfocito T CD4 Linfocito T Molécula coestimulatoria Tratamiento Transducción señal Cáncer Citoquina Hemopatía maligna Retroviridae Virus
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R03 Immunotherapy

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis

Discipline
Blood diseases Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
21853998

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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