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Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor

Author
BAN, Maria1 ; GORIS, An2 ; DUBOIS, Bénédicte2 ; HARBO, Hanne F3 ; CELIUS, Elisabeth G3 ; SPURKLAND, Anne8 ; STRANGE, Richard5 ; HAWKINS, Clive5 ; ROBERTSON, Neil P6 ; DUDBRIDGE, Frank9 ; WASON, James9 ; DE JAGER, Philip L10 11 ; LORENTZEN, Aslaug R3 4 ; HAFLER, David11 ; RIOUX, John D12 ; IVINSON, Adrian J13 ; MCCAULEY, Jacob L14 ; PERICAK-VANCE, Margaret14 ; OKSENBERG, Jorge R15 ; HAUSER, Stephen L15 ; SEXTON, David16 ; HAINES, Jonathan16 ; SAWCER, Stephen1 ; BAKER, Amie1 ; MIHALOVA, Tania5 ; INGRAM, Gillian6 ; BOOTH, David R7 ; HEARD, Robert N7 ; STEWART, Graeme J7 ; BOGAERT, Elke2
[1] Department of Clinical Neuroscience, Addenbrooke's, Hospital, University of Cambridge, Cambridge, United Kingdom
[2] Section for Experimental Neurology, Katholieke Universiteit Leuven, Leuven, Belgium
[3] Department of Neurology, Faculty Division Ullevdl University Hospital, University of Oslo, Oslo, Norway
[4] Institute of Immunology, Rikshospitalet University Hospital, Oslo, Norway
[5] Department of Neurology, Keele University Medical School, Hartshill Campus, Stoke on Trent, United Kingdom
[6] Department of Neurology, University Hospital of Wales, Heath Park, Cardiff, United Kingdom
[7] Institute for Immunology and Allergy Research, Westmead Millennium Institute, Westmead Hospital, University of Sydney, New South Wales, Australia
[8] Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
[9] MRC Biostatistics Unit, Cambridge, United Kingdom
[10] Harvard Medical School/Partners Healthcare Center for Genetics and Genomics, Boston, MA, United States
[11] Division of Molecular Immunology, Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, United States
[12] Broad Institute of Harvard University and Massachusetts Institute of Technology, Cambridge, MA, United States
[13] Harvard NeuroDiscovery Center, Harvard Medical School, Boston, MA, United States
[14] University of Miami School of Medicine, Miami, FL, United States
[15] Department of Neurology, University of California San Francisco, San Francisco, CA, United States
[16] Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, TN, United States
Wellcome Trust Case-Control Consortium (WTCCC) and Alastair Compston, United Kingdom
Source

European journal of human genetics. 2009, Vol 17, Num 10, pp 1309-1313, 5 p ; ref : 34 ref

ISSN
1018-4813
Scientific domain
Genetics
Publisher
Nature Publishing Group, Basingstoke
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
TYK2 multiple sclerosis
Keyword (fr)
Facteur risque Génétique Réplication Sclérose en plaques Maladie inflammatoire Pathologie du système nerveux central Pathologie du système nerveux
Keyword (en)
Risk factor Genetics Replication Multiple sclerosis Inflammatory disease Central nervous system disease Nervous system diseases
Keyword (es)
Factor riesgo Genética Replicación Esclerosis en placa Enfermedad inflamatoria Sistema nervosio central patología Sistema nervioso patología
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology

Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A07 Genetics of eukaryotes. Biological and molecular evolution

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17F Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B23 Medical genetics / 002B23A General aspects. Genetic counseling

Discipline
Eukaryotes genetics. Biological and molecular evolution Medical genetics Molecular and cell biology Neurology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
21933499

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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