Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors
- Author
- DASSIE, Justin P1 2 ; LIU, Xiu-Ying1 ; THOMAS, Gregory S1 2 ; WHITAKER, Ryan M1 ; THIEL, Kristina W1 ; STOCKDALE, Katie R1 ; MEYERHOLZ, David K3 ; MCCAFFREY, Anton P1 2 ; MCNAMARA, James O1 ; GIANGRANDE, Paloma H1 2 4
[1] Department of Internal Medicine, University of Iowa, Iowa City, Iowa, United States
[2] Molecular and Cellular Biology Program, University of Iowa, Iowa City, Iowa, United States
[3] Departrnent of Pathology, University of Iowa, Iowa City, Iowa, United States
[4] Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, United States - Source
Nature biotechnology (Print). 2009, Vol 27, Num 9, pp 839-846, 8 p ; ref : 47 ref
- CODEN
- NABIF9
- ISSN
- 1087-0156
- Scientific domain
- Biotechnology
- Publisher
- Nature Publishing Group, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- ARNsi Anticancéreux Antigène membranaire spécifique prostate Aptamère Cancer de la prostate Interférence ARN Optimisation Souris Tumeur Voie générale Mammalia Rodentia Silence expression génique Vertebrata
- Keyword (en)
- siRNA Antineoplastic agent Prostate specific membrane antigen Aptamer Prostate cancer RNA interference Optimization Mouse Tumor Systemic route Mammalia Rodentia Gene silencing Vertebrata
- Keyword (es)
- ARNsi Anticanceroso Antígeno membranar específico prostata Aptómero Cáncer de la próstata ARN interferencia Optimización Ratón Tumor Vía general Mammalia Rodentia Silencio expresión genética Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A31 Biotechnology / 002A31D Industrial applications and implications. Economical aspects / 002A31D01 Health. Pharmaceutical industry / 002A31D01G Miscellaneous
- Discipline
- Biotechnology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 21933925
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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