Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer
- Author
- SOUGLAKOS, J1 2 ; PHILIPS, J3 ; FREED, E3 ; MEYERHARDT, J. A3 8 ; SARIDAKI, Z2 ; GEORGOULIAS, V1 2 ; FINKELSTEIN, D4 ; FUCHS, C. S3 8 ; KULKE, M. H3 8 ; SHIVDASANI, R. A3 8 ; WANG, R4 ; MARWAH, S3 ; SILVER, M4 ; TZARDI, M5 ; SILVER, J3 ; OGINO, S3 6 ; HOOSHMAND, S3 ; KWAK, E7 8
[1] Department of Medical Oncology, University Hospital, Heraklion, Crete, Greece
[2] Laboratory of Tumor Biology, University of Crete, Heraklion, Crete, Greece
[3] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States
[4] Department of Biostatistics, Massachusetts General Hospital, Boston, Massachusetts, United States
[5] Department of Pathology, Laboratory of Pathology, University Hospital, Heraklion, Crete, Greece
[6] Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, United States
[7] Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States
[8] Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States - Source
British journal of cancer. 2009, Vol 101, Num 3, pp 465-472, 8 p ; ref : 3/4 p
- CODEN
- BJCAAI
- ISSN
- 0007-0920
- Scientific domain
- Medical oncology
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- BRAF KRAS PIK3CA metastatic CRC mutation prediction
- Keyword (fr)
- 1-Phosphatidylinositol 3-kinase Cancer colorectal Cancérologie Efficacité traitement Facteur prédictif Gène K ras Gène onc cellulaire Génétique Homme Mutation Métastase Pronostic Protooncogène Stade avancé Survie Valeur prédictive Gène BRAF Cancer Enzyme Pathologie de l'appareil digestif Pathologie de l'intestin Pathologie du côlon Pathologie du rectum Transferases Tumeur maligne
- Keyword (en)
- 1-Phosphatidylinositol 3-kinase Colorectal cancer Cancerology Treatment efficiency Predictive factor K ras Gene C-Onc gene Genetics Human Mutation Metastasis Prognosis Protooncogene Advanced stage Survival Predictive value BRAF Gene Cancer Enzyme Digestive diseases Intestinal disease Colonic disease Rectal disease Transferases Malignant tumor
- Keyword (es)
- 1-Phosphatidylinositol 3-kinase Cancer de colon y recto Cancerología Eficacia tratamiento Factor predictivo Gen K ras Gen onc celular Genética Hombre Mutación Metástasis Pronóstico Protooncogen Estadio avanzado Sobrevivencia Valor predictivo Gen BRAF Cáncer Enzima Aparato digestivo patología Intestino patología Colón patología Recto patología Transferases Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13B Stomach. Duodenum. Small intestine. Colon. Rectum. Anus / 002B13B01 Tumors
- Discipline
- Gastroenterology. Liver. Pancreas. Abdomen Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 21938165
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.bjc.6605164 
https://dx.doi.org/10.1038/sj.bjc.6605164
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