Effect of β2,-adrenergic receptor polymorphism on response to longacting β2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trial
- Author
- WECHSLER, Michael E1 ; KUNSELMAN, Susan J2 ; FAHY, John V4 ; JARJOUR, Nizar7 ; KAZANI, Shamsah1 ; KIM, Sophia1 ; KRAFT, Monica8 ; LAZARUS, Stephen C4 ; LEMANSKE, Robert F7 ; MARKEZICH, Amy1 ; MARTIN, Richardj9 ; PERMAUL, Perdita1 ; CHINCHILLI, Vernon M2 ; PETERS, Stephen P3 ; RAMSDELL, Joe10 ; SORKNESS, Christine A7 ; RAND SUTHERLAND, E9 ; SZEFLER, Stanleyj9 ; WALTER, Michael J6 ; WASSERMAN, Stephen I10 ; ISRAEL, Elliot1 ; BLEECKER, Eugene3 ; BOUSHEY, Homer A4 ; CALHOUN, William J5 ; AMEREDES, Bill T5 ; CASTRO, Mario6 ; CRAIG, Timothyj2 ; DENLINGER, Loren7
[1] Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States
[2] Penn StateCollege of Medicine, Hershey, PA, United States
[3] Wake Forest University Health Science Center, Winston-Salem, NC, United States
[4] University of California, San Francisco Medical Center, San Francisco, CA, United States
[5] University ofTexas, Galveston,TX, United States
[6] Washington University School of Medicine, St Louis, MO, United States
[7] University of Wisconsin-Madison, Madison, WI, United States
[8] Duke University Medical Center, Durham, NC, United States
[9] National Jewish Medical Center, Denver, CO, United States
[10] University of California, San Diego Medical Center, San Diego, CA, United States
National Heart, Lung, and Blood Institute's Asthma Clinical Research Network, United States - Source
Lancet (British edition). 2009, Vol 374, Num 9703, pp 1754-1764, 11 p ; ref : 26 ref
- CODEN
- LANCAO
- ISSN
- 0140-6736
- Scientific domain
- General medicine general surgery
- Publisher
- Elsevier, Kidlington
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Agoniste Asthme Essai clinique Génotype Médecine Placebo Polymorphisme Récepteur β2-adrénergique Typage Variabilité génétique Essai randomisé contrôlé Bronchopneumopathie obstructive Pathologie de l'appareil respiratoire Pathologie des bronches Pathologie des poumons
- Keyword (en)
- Agonist Asthma Clinical trial Genotype Medicine Placebo Polymorphism β2-Adrenergic receptor Typing Genetic variability Randomized controlled trial Obstructive pulmonary disease Respiratory disease Bronchus disease Lung disease
- Keyword (es)
- Agonista Asma Ensayo clínico Genotipo Medicina Placebo Polimorfismo Receptor β2-adrenérgico Tipificación Variabilidad genética Ensayo aleatorio controlado Enfermedad pulmonar obstructiva Aparato respiratorio patología Bronquio patología Pulmón patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11B Chronic obstructive pulmonary disease, asthma
- Discipline
- Generalities in medical sciences Pulmonology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22153869
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0140-6736(09)61492-6 
https://dx.doi.org/10.1016/S0140-6736(09)61492-6
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