Multitargeted tyrosine kinase inhibitor stimulates expression of IL-6 and activates JAK2/STAT5 signaling in acute myelogenous leukemia cells
- Author
- NISHIOKA, C1 2 ; IKEZOE, T1 ; YANG, J1 ; YOKOYAMA, A1
[1] Department of Hematology and Respiratory Medicine, Kochi Medical School, Kochi University, Nankoku, Kochi, Japan
[2] Research Fellow for Young Scientists from the Japan Society for the Promotion of Science (JSPS), Chiyodaku, Tokyo, Japan - Source
Leukemia. 2009, Vol 23, Num 12, pp 2304-2308, 5 p ; ref : 4 ref
- CODEN
- LEUKED
- ISSN
- 0887-6924
- Scientific domain
- Medical oncology; Hematology
- Publisher
- Nature Publishing Group, Avenel, NJ
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Facteur transcription STAT5 Hématologie Inhibiteur de la tyrosine kinase Inhibiteur multikinase Interleukine 6 Leucémie aiguë myéloblastique Protein-tyrosine kinase Transduction signal JAK2 protein tyrosine kinase Cancer Cytokine Enzyme Hémopathie maligne Transferases
- Keyword (en)
- Transcription factor STAT5 Hematology Tyrosine kinase inhibitor Multikinase inhibitor Interleukin 6 Acute myelogenous leukemia Protein-tyrosine kinase Signal transduction JAK2 protein tyrosine kinase Cancer Cytokine Enzyme Malignant hemopathy Transferases
- Keyword (es)
- Factor transcripción STAT5 Hematología Inhibidor tyrosine kinase inhibidor multicinasa Interleuquina 6 Leucemia aguda mieloblástica Protein-tyrosine kinase Transducción señal JAK2 protein tyrosine kinase Cáncer Citoquina Enzima Hemopatía maligna Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
- Discipline
- Blood diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22355627
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/leu.2009.163 
https://dx.doi.org/10.1038/leu.2009.163
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