Heat Shock Protein 90: Inhibitors in Clinical Trials
- Author
- BIAMONTE, Marco A1 ; VAN DE WATER, Ryan1 ; ARNDT, Joseph W2 ; SCANNEVIN, Robert H2 ; PERRET, Daniel1 ; LEE, Wen-Cherng1
[1] Riogen Idec, 5200 Research Place, San Diego, California 92122, United States
[2] Riogen Idec, Cambridge, Massachusetts 02142, United States - Source
Journal of medicinal chemistry (Print). 2010, Vol 53, Num 1, pp 3-17, 15 p ; ref : 97 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Columbus, OH
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Adenosinetriphosphatase Animal Anticancéreux Article synthèse Carboxamide Cellule tumorale Chaperon Dérivé de la benzamide Dérivé de la purine Dérivé du résorcinol Essai clinique Essai préclinique Estomac Glande mammaire Glioblastome Inhibiteur enzyme Lactame Macrocycle Mode liaison Modèle moléculaire Modélisation Ovaire Pancréas Pharmacocinétique Prostate Protéine choc thermique Protéine de choc thermique 90 Quinone Souris Transduction signal Voie orale Geldanamycine dérivé Enzyme Hydrolases Mammalia Rodentia Vertebrata
- Keyword (en)
- Adenosinetriphosphatase Animal Antineoplastic agent Review Carboxamide Tumor cell Chaperone Benzamide derivatives Purine derivatives Resorcinol derivatives Clinical trial Preclinical trial Stomach Mammary gland Glioblastoma Enzyme inhibitor Lactam Macrocycle Binding mode Molecular model Modeling Ovary Pancreas Pharmacokinetics Prostate Heat shock protein Heat shock protein 90 Quinone Mouse Signal transduction Oral administration Enzyme Hydrolases Mammalia Rodentia Vertebrata
- Keyword (es)
- Adenosinetriphosphatase Animal Anticanceroso Artículo síntesis Carboxamida Célula tumoral Chaperone Benzamida derivado Purina derivado Resorcinol derivado Ensayo clínico Ensayo preclínico Estómago Glándula mamaria Glioblastoma Inhibidor enzima Lactamo Macrociclo Modo de enlace Modelo molecular Modelización Ovario Páncreas Farmacocinética Prostata Proteína choque térmico Proteína de choque térmico 90 Quinona Ratón Transducción señal Vía oral Enzima Hydrolases Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22361867
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm9004708 
https://dx.doi.org/10.1021/jm9004708
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