Metal-based biologically active agents: Synthesis, characterization, antibacterial and antileukemia activity evaluation of Cu(II), V(IV) and Ni(II) complexes with antipyrine-derived compounds
- Author
- ROSU, Tudor1 ; NEGOIU, Maria1 ; PASCULESCU, Simona1 ; PAHONTU, Elena1 ; POIRIER, Donald3 ; GULEA, Aurelian2
[1] Inorganic Chemistry Department, Faculty of Chemistry, University of Bucharest, 23 Dumbrava Rosie Street, 020462 Bucharest, Romania
[2] Coordination Chemistry Department, Moldova State University, 60 Mateevici Street, Kishinev, Moldavia, United States
[3] Oncology and Molecular Endocrinology Research Center CHUL, Research Center and Universite Laval, CHUQ-CHUL, 2705 Boulevard Laurier, Quebec City G1V4G2, Canada - Source
European journal of medicinal chemistry. 2010, Vol 45, Num 2, pp 774-781, 8 p ; ref : 42 ref
- CODEN
- EJMCA5
- ISSN
- 0223-5234
- Scientific domain
- Organic chemistry; Pharmacology drugs
- Publisher
- Elsevier, Kidlington
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Antimicrobial activity Antipyrine Copper complexes Leukemia cells HL-60 Schiff bases
- Keyword (fr)
- Aldimine Antibactérien Anticancéreux Antifongique Antimicrobien Base Schiff Candida albicans Cellule tumorale Coordinat organique Cuivre II Complexe Cytotoxicité Diphénols Dérivé du benzaldéhyde Escherichia coli Homme Imine In vitro Leucémie promyélocytaire Lignée HL60 Lignée cellulaire Métal tétravalent Complexe Nickel II Complexe Phénols Relation structure activité Staphylococcus aureus Synthèse chimique Vanadium IV Complexe Vanadyle Complexe Antipyrine dérivé Isophtalaldéhyde dérivé Phénazone dérivé Bactérie Dérivé du pyrazole Enterobacteriaceae Fungi Imperfecti Fungi Micrococcaceae Micrococcales Métal divalent Complexe Métal transition Complexe
- Keyword (en)
- Aldimine Antibacterial agent Antineoplastic agent Antifungal agent Antimicrobial agent Schiff base Candida albicans Tumor cell Organic ligand Copper II Complexes Cytotoxicity Diphenols Benzaldehyde derivatives Escherichia coli Human Imine In vitro Promyelocytic leukemia HL60 cell line Cell line Tetravalent metal Complexes Nickel II Complexes Phenols Structure activity relation Staphylococcus aureus Chemical synthesis Vanadium IV Complexes Vanadyl Complexes Bacteria Pyrazole derivatives Enterobacteriaceae Fungi Imperfecti Fungi Micrococcaceae Micrococcales Divalent metal Complexes Transition metal Complexes
- Keyword (es)
- Aldimina Antibacteriano Anticanceroso Antifúngico Antimicrobiano Base Schiff Candida albicans Célula tumoral Ligando orgánico Cobre II Complejo Citotoxicidad Difenoles Benzaldehído derivado Escherichia coli Hombre Imina In vitro Leucemia promielocítica Línea HL60 Línea celular Metal tetravalente Complejo Niquel II Complejo Fenoles Relación estructura actividad Staphylococcus aureus Síntesis química Vanadio IV Complejo Vanadilo Complejo Bacteria Pirazol derivado Enterobacteriaceae Fungi Imperfecti Fungi Micrococcaceae Micrococcales Metal divalente Complejo Metal transición Complejo
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S01 General aspects
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S02 Antibacterial agents
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S04 Antifungal agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22383563
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.ejmech.2009.10.034 
https://dx.doi.org/10.1016/j.ejmech.2009.10.034
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