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Interleukin-15 enhances natural killer cell cytotoxicity in patients with acute myeloid leukemia by upregulating the activating NK cell receptors

Author
SZCZEPANSKI, Miroslaw J1 ; SZAJNIK, Marta1 ; WELSH, Ann1 ; FOON, Kenneth A1 ; WHITESIDE, Theresa L2 ; BOYIADZIS, Michael1
[1] Division of Hematology-Oncology, Department of Medicine, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, 5150 Centre Avenue, Suite 572, Pittsburgh, PA 15232, United States
[2] Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States
Source

Cancer immunology and immunotherapy. 2010, Vol 59, Num 1, pp 73-79, 7 p ; ref : 26 ref

CODEN
CIIMDN
ISSN
0340-7004
Scientific domain
Biochemistry, molecular biology, biophysics; Medical oncology; Immunology, immunopathology, allergology
Publisher
Springer, Heidelberg
Publication country
Germany
Document type
Article
Language
English
Author keyword
Activating receptors Acute myeloid leukemia Interleukin -15 NCRs NKG2D Natural killer cells
Keyword (fr)
Cellule NK Cytokine Cytotoxicité Homme Immunothérapie Interleukine 15 Leucémie aiguë myéloblastique Malade Récepteur biologique Traitement Récepteur NCR Récepteur NKG2D Cancer Hémopathie maligne
Keyword (en)
Natural killer cell Cytokine Cytotoxicity Human Immunotherapy Interleukin 15 Acute myelogenous leukemia Patient Biological receptor Treatment Natural cytotoxicity receptor NKG2D receptor Cancer Malignant hemopathy
Keyword (es)
Célula NK Citoquina Citotoxicidad Hombre Inmunoterapia Interleuquina 15 Leucemia aguda mieloblástica Enfermo Receptor biológico Tratamiento Cáncer Hemopatía maligna
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R03 Immunotherapy

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis

Discipline
Blood diseases Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
22530674

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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