Therapeutic antibody targeting of individual Notch receptors
- Author
- YAN WU1 ; CAIN-HOM, Carol2 ; SCHAHIN-REED, Dorreyah6 ; DOW, Graham J2 ; SHELTON, Amy2 ; STAWICKI, Scott1 ; WATTS, Ryan J6 ; ZHANG, Jeff8 ; CHOY, Robert8 ; HOWARD, Peter8 ; KADYK, Lisa8 ; MINHONG YAN5 ; CHOY, Lisa2 ; JIPING ZHA3 ; CALLAHAN, Christopher A3 ; HYMOWITZ, Sarah G7 ; SIEBEL, Christian W2 ; HAGENBEEK, Thijs J2 ; DE LEON, Gladys P7 ; YONGMEI CHEN1 ; FINKLE, David4 ; VENOOK, Rayna4 ; XIUMIN WU5 ; RIDGWAY, John5
[1] Department of Antibody Engineering, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States
[2] Department of Molecular Biology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States
[3] Department of Pathology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States
[4] Department of Translational Oncology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States
[5] Department of Tumor Biology and Angiogenesis, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States
[6] Department of Neurodegeneration, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States
[7] Department of Structural Biology, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States
[8] Exelixis Inc., 210 East Grand Avenue, PO Box 511, South San Francisco, California 94083-0511, United States - Source
Nature (London). 2010, Vol 464, Num 7291, pp 1052-1057, 6 p ; ref : 30 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Anticorps monoclonal Homme Leucémie aiguë lymphoblastique Récepteur biologique Thérapeutique ciblée Traitement Récepteur Notch Cancer Hémopathie maligne Syndrome lymphoprolifératif
- Keyword (en)
- Monoclonal antibody Human Acute lymphocytic leukemia Biological receptor Targeted therapy Treatment Notch receptor Cancer Malignant hemopathy Lymphoproliferative syndrome
- Keyword (es)
- Anticuerpo monoclonal Hombre Leucemia aguda linfoblástica Receptor biológico Terapéutica dirigida Tratamiento Receptor Notch Cáncer Hemopatía maligna Linfoproliferativo síndrome
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
- Discipline
- Blood diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22602043
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature08878 
https://dx.doi.org/10.1038/nature08878
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