Genome-wide association identifies multiple ulcerative colitis susceptibility loci

Author

MCGOVERN, Dermot P. B¹ ; GARDET, Agnès² ; GREEN, Todd⁸ ; STEVENS, Christine R⁸ ; BEAUCHAMP, Claudine⁴ ; FLESHNER, Phillip R¹ ; CARLSON, Marie⁹ ; D'AMATO, Mauro¹⁰ ; HALFVARSON, Jonas¹¹ ; HIBBERD, Martin L¹² ; LÖRDAL, Mikael¹³ ; PADYUKOV, Leonid¹⁴ ; TÖRKVIST, Leif³ ; ANDRIULLI, Angelo¹⁵ ; COLOMBO, Elisabetta¹⁵ ; LATIANO, Anna¹⁵ ; PALMIERI, Orazio¹⁵ ; BERNARD, Edmond-Jean¹⁶ ; DESLANDRES, Colette¹⁷ ; HOMMES, Daan W¹⁸ ; DE JONG, Dirk J¹⁹ ; STOKKERS, Pieter C²⁰ ; WEERSMA, Rinse K²¹ ; GOYETTE, Philippe⁴ ; SHARMA, Yashoda²² ; SILVERBERG, Mark S²³ ; CHO, Judy H^{22 24} ; JING WU; ROEDER, Kathryn; BRANT, Steven R; SCHUMM, L. Phillip; DUERR, Richard H; DUBINSKY, Marla C¹ ; GLAZER, Nicole L; ESSERS, Jonah⁵ ; HARITUNIANS, Talin⁶ ; IPPOLITI, Andy¹ ; MELMED, Gil Y¹ ; SISCOVICK, David S; VASILIAUSKAS, Eric A¹ ; TARGAN, Stephan R¹ ; ANNESE, Vito¹⁵ ; WIJMENGA, Cisca; PETTERSSON, Sven; ROTTER, Jerome I⁶ ; TAYLOR, Kent D⁶ ; XAVIER, Ramnik J^{2 8} ; DALY, Mark J^{5 8} ; RIOUX, John D⁴ ; SEIELSTAD, Mark⁷ ; NEATER, Benjamin M⁵ ; ONG, Rick T. H⁷ ; LAGACE, Caroline⁴ ; CHUN LI²
[1] Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States
[2] Center for Computational and Integrative Biology and Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States
[3] Department for Clinical Science Intervention and Technology, Karolinska Institutet and IBD Clinical Research Group at Karolinska University Hospital, Stockholm, Sweden
[4] Université de Montréal and the Montreal Heart Institute, Research Center, Montréal, Québec, Canada
[5] Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States
[6] Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States
[7] Human Genetics, Genome Institute of Singapore, Singapore
[8] The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States
[9] Department of Medical Sciences, Gastroenterology Research Group, Uppsala University Hospital, Uppsala, Sweden
[10] Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden
[11] Division of Gastroenterology, Department of Internal Medicine, Orebro University Hospital, Orebro, Sweden
[12] Infectious Diseases, Genome Institute of Singapore, Singapore
[13] Department of Medicine, and IBD Clinical Research Group at Karolinska University Hospital, Stockholm, Sweden
[14] Rheumatology Unit, Department of Medicine, Karolinska Institutet at Karolinska University Hospital Solna, Stockholm, Sweden
[15] Gastroenterologia ed Endoscopia Digestiva, Ospedale'Casa Sollievo della Sofferenza', Istituto di Ricovero e Cura a Carattere Scientifico, San Giovanni Rotondo, Italy
[16] Université de Montréal and Centre Hospitalier Universitaire de l'Université de Montréal, Montréal, Québec, Canada
[17] Department of Gastroenterology, Hôpital Sainte-Justine, Montréal, Québec, Canada
[18] Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, Netherlands
[19] Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
[20] Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, Netherlands
[21] Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands
[22] Section of Digestive Diseases, Department of Medicine, Yale University, New Haven, Connecticut, United States
[23] Mount Sinai Hospital Inflammatory Bowel Disease Group, University of Toronto, Toronto, Ontario, Canada
[24] Department of Genetics, Yale University, New Haven, Connecticut, United States

Source

Nature genetics. 2010, Vol 42, Num 4, pp 332-337, 6 p ; ref : 24 ref

CODEN

NGENEC

ISSN

1061-4036

Scientific domain

Genetics

Publisher

Nature Publishing Group, New York, NY

Publication country

United States

Document type

Article

Language

English

Keyword (fr)

Identification Locus Rectocolite ulcérohémorragique Association génétique Echelle du génome Maladie inflammatoire Pathologie de l'appareil digestif Pathologie de l'intestin

Keyword (en)

Identification Locus Ulcerative colitis Inflammatory disease Digestive diseases Intestinal disease

Keyword (es)

Identificación Locus Rectocolitis ulcerohemorrágica Enfermedad inflamatoria Aparato digestivo patología Intestino patología

Classification

Pascal

002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A07 Genetics of eukaryotes. Biological and molecular evolution

Pascal

002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13B Stomach. Duodenum. Small intestine. Colon. Rectum. Anus / 002B13B03 Other diseases. Semiology

Discipline

Eukaryotes genetics. Biological and molecular evolution Gastroenterology. Liver. Pancreas. Abdomen

Origin

Inist-CNRS

Database

PASCAL

INIST identifier

22629267

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS