Thousands of chemical starting points for antimalarial lead identification
- Author
- GAMO, Francisco-Javier1 ; SANZ, Laura M1 ; BROWN, James R4 ; PEISHOFF, Catherine E5 ; CARDON, Lon R6 ; GARCIA-BUSTOS, Jose F1 ; VIDAL, Jaume1 ; DE COZAR, Cristina1 ; ALVAREZ, Emilio1 ; LAVANDERA, Jose-Luis1 ; VANDERWALL, Dana E2 ; GREEN, Darren V. S3 ; KUMAR, Vinod4 ; HASAN, Samiul4
[1] Tres Cantos Medicines Development Campus, GlaxoSmithKline, Severo Ochoa 2, 28760 Tres Cantos, Spain
[2] Computational and Structural Chemistry, GlaxoSmithKline, Five Moore Drive, Research Triangle Park, North Carolina 27709-3398, United States
[3] Computational and Structural Chemistry, GlaxoSmithKline, Medicines Research Centre, Gunnels Wood Road, Hertfordshire, Stevenage SG1 2NY, United Kingdom
[4] Computational Biology, Quantitative Sciences, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States
[5] Computational and Structural Chemistry, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States
[6] Quantitative Sciences, GlaxoSmithKline, 709 Swedeland Road, King of Prussia, Pennsylvania 19406, United States - Source
Nature (London). 2010, Vol 465, Num 7296, pp 305-310, 6 p ; ref : 27 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Analyse chimique Antipaludique Antiparasitaire Association médicamenteuse Homme Identification Mécanisme action Médicament Paludisme Pharmacothérapie Plasmodium falciparum Protéine Résistance traitement Apicomplexa Infection Parasitose Protozoa Protozoose Traitement
- Keyword (en)
- Chemical analysis Antimalarial Parasiticide Drug combination Human Identification Mechanism of action Drug Malaria Pharmacotherapy Plasmodium falciparum Protein Treatment resistance Apicomplexa Infection Parasitosis Protozoa Protozoal disease Treatment
- Keyword (es)
- Análisis químico Antipalúdico Antiparasitario Asociación medicamentosa Hombre Identificación Mecanismo acción Medicamento Paludismo Farmacoterapia Plasmodium falciparum Proteína Resistencia tratamiento Apicomplexa Infección Parasitosis Protozoa Protozoosis Tratamiento
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B05 Infectious diseases / 002B05E Parasitic diseases / 002B05E01 General aspects
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B05 Infectious diseases / 002B05E Parasitic diseases / 002B05E02 Protozoal diseases / 002B05E02B Human protozoal diseases / 002B05E02B4 Malaria
- Discipline
- Infectious pathology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 22770008
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature09107 
https://dx.doi.org/10.1038/nature09107
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