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Loss of poly(ADP-ribose) polymerase-2 leads to rapid development of spontaneous T-cell lymphomas in p53-deficient mice

Author
NICOLAS, L1 2 ; MARTINEZ, C3 ; APARICIO, P2 ; YELAMOS, J1 ; BARO, C4 ; RODRIGUEZ, M4 ; BAROJA-MAZO, A3 ; SOLE, F4 ; FLORES, J. M5 ; AMPURDANES, C1 ; DANTZER, F6 ; MARTIN-CABALLERO, J1
[1] Department of Immunology, IMIM-Hospital del Mar, Barcelona Biomedical Research Park, Barcelona, Spain
[2] Department of Biochemistry, Molecular Biology and Immunology, School of Medicine, University of Murcia, Murcia, Spain
[3] Department of Surgery, CIBERehd, University Hospital 'Virgen de la Arrixaca', University of Murcia, Murcia, Spain
[4] Department of Pathology, IMIM-Hospital del Mar, Barcelona Biomedical Research Park, Barcelona, Spain
[5] Department of Animal Surgery and Medicine, School of Veterinary, University Complutense of Madrid, Madrid, Spain
[6] IREBS-FRE3211, ESBS, bld Sébastien Brant, Strasbourg, France
Source

Oncogene (Basingstoke). 2010, Vol 29, Num 19, pp 2877-2883, 7 p ; ref : 1 p

ISSN
0950-9232
Scientific domain
Cell biology, histology; Medical oncology; Genetics
Publisher
Nature Publishing Group, Basingstoke
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
Parp-2 V(D)J recombination double-strand breaks p53 thymocytes tumour development
Keyword (fr)
Carcinogenèse Cassure bicaténaire Développement Gène TP53 Gène suppresseur tumeur Lymphocyte T Lymphome NAD+ ADP-ribosyltransferase Recombinaison Souris Spontané Thymocyte Tumeur Cancer Enzyme Glycosyltransferases Hémopathie maligne Mammalia Pentosyltransferases Rodentia Syndrome lymphoprolifératif Transferases Vertebrata
Keyword (en)
Carcinogenesis Double strand break Development TP53 Gene Tumor suppressor gene T-Lymphocyte Lymphoma NAD+ ADP-ribosyltransferase Recombination Mouse Spontaneous Thymocyte Tumor Cancer Enzyme Glycosyltransferases Malignant hemopathy Mammalia Pentosyltransferases Rodentia Lymphoproliferative syndrome Transferases Vertebrata
Keyword (es)
Carcinogénesis Ruptura bicatenaria Desarrollo Gen TP53 Gen supresor tumor Linfocito T Linfoma NAD+ ADP-ribosyltransferase Recombinación Ratón Espontáneo Timocito Tumor Cáncer Enzima Glycosyltransferases Hemopatía maligna Mammalia Pentosyltransferases Rodentia Linfoproliferativo síndrome Transferases Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04C Molecular genetics / 002A04C08 Genic rearrangement. Recombination. Transposable element

Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H04 Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis

Discipline
Blood diseases Molecular and cell biology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
22782737

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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