Rapid and Label-Free Screening of Enzyme Inhibitors Using Segmented Flow Electrospray Ionization Mass Spectrometry
- Author
- JIAN PE1 ; QIANG LI1 ; KENNEDY, Robert T1 2
[1] Department of Chemistry, University of Michigan, Ann Arbor, Michigan, United States
[2] Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, United States - Source
Journal of the American Society for Mass Spectrometry. 2010, Vol 21, Num 7, pp 1107-1113, 7 p ; ref : 37 ref
- ISSN
- 1044-0305
- Scientific domain
- Biochemistry, molecular biology, biophysics; Analytical chemistry; Organic chemistry
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Keyword (fr)
- Acetylcholinesterase Anticholinestérasique Criblage haut débit Electrospray Inhibiteur enzyme Injection en écoulement Spectrométrie masse Inhibiteur acetylcholinesterase Injection à écoulement segmenté Carboxylic ester hydrolases Enzyme Esterases Hydrolases
- Keyword (en)
- Acetylcholinesterase Anticholinesterase agent High throughput screening Electrospray Enzyme inhibitor Flow injection Mass spectrometry Carboxylic ester hydrolases Enzyme Esterases Hydrolases
- Keyword (es)
- Acetylcholinesterase Anticolinesterasa agente Cribado alta productividad Electrospray Inhibidor enzima Inyección flujo Espectrometría masa Carboxylic ester hydrolases Enzima Esterases Hydrolases
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry / 002A02E Enzymes and enzyme inhibitors / 002A02E04 Hydrolases
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02W Miscellaneous
- Discipline
- Analytical, structural and metabolic biochemistry General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 23010865
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.jasms.2010.02.013 
https://dx.doi.org/10.1016/j.jasms.2010.02.013
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