Synthesis and Preliminary Screening of Novel Tryptamines as 5-HT4 Receptor Ligands
- Author
- HANNA-ELIAS, A1 ; MANALLACK, D. T1 ; BERQUE-BESTEL, I2 3 ; IRVING, H. R1 ; COUPAR, I. M1 ; ISKANDER, M. N1
[1] Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Vic. 3053, Australia
[2] Univ Paris-Sud, BioCIS UMR 8076, Laboratoire de Chimie Thérapeutique, Faculté de Pharmacie, rue J.B. Clément, 92296 Châtenay-Malabry, France
[3] Inserm U869, Université Victor Segalen, 146 rue léo Saignat, 33076 Bordeaux, France - Source
Current medicinal chemistry. 2010, Vol 17, Num 25, pp 2775-2787, 13 p ; ref : 26 ref
- ISSN
- 0929-8673
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Bentham, Oak Park, IL
- Publication country
- United States
- Document type
- Article
- Language
- English
- Author keyword
- 5-HT4 ligands 5-HT4 receptor medicinal chemistry serotonin tryptamine
- Keyword (fr)
- Affinité Agoniste Composé aromatique Composé bicyclique Criblage Dérivé de la tryptamine Ether Hétérocycle azote In vitro Modèle moléculaire Modélisation Relation structure activité Récepteur sérotoninergique 5-HT4 Synthèse chimique Sérotonine Indole(5-méthoxy-3-[2-([3,4,5-triméthoxybenzyl]amino)éthyl])
- Keyword (en)
- Affinity Agonist Aromatic compound Bicyclic compound Screening Tryptamine derivatives Ether Nitrogen heterocycle In vitro Molecular model Modeling Structure activity relation 5-HT4 Serotonine receptor Chemical synthesis Serotonin
- Keyword (es)
- Afinidad Agonista Compuesto aromático Compuesto bicíclico Cernido Eter Heterociclo nitrógeno In vitro Modelo molecular Modelización Relación estructura actividad Receptor serotoninérgico 5-HT4 Síntesis química Serotonina
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09C Serotoninergic system
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 23146220
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.2174/092986710791859351 
https://dx.doi.org/10.2174/092986710791859351
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