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Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial

Author
GREENWAY, Frank L1 ; FUJIOKA, Ken2 ; PLODKOWSKI, Raymond A3 ; MUDALIAR, Sunder4 ; GUTTADAURIA, Maria5 6 ; ERICKSON, Janelle1 ; KIM, Dennis D7 ; DUNAYEVICH, Eduardo7
[1] Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA, United States
[2] Scripps Clinic, La Jolla, CA, United States
[3] University of Nevada School of Medicine and Reno Veterans Affairs Medical Center, Sierra Nevada Health Care System, Reno, NV, United States
[4] Veterans Affairs San Diego Healthcare System and Department of Medicine, University of California, San Diego, CA, United States
[5] MG Consulting, New York, NY, United States
[6] inVentiv Clinical Solutions, Baltimore, MD, United States
[7] Orexigen Therapeutics, La Jolla, CA, United States
COR-I Study Group, United States
Source

Lancet (British edition). 2010, Vol 376, Num 9741, pp 595-605, 11 p ; ref : 33 ref

CODEN
LANCAO
ISSN
0140-6736
Scientific domain
General medicine general surgery
Publisher
Elsevier, Kidlington
Publication country
United Kingdom
Document type
Article
Language
English
Keyword (fr)
Adulte Antagoniste analgésique narcotique Association médicamenteuse Bupropione Essai clinique phase III Essai clinique Etat nutritionnel Etude multicentrique Médecine Naltrexone Obésité Perte poids Placebo Poids corporel Psychotrope Randomisation Sevrage toxique Surcharge pondérale Toxicomanie Biométrie corporelle Dérivé du morphinane Homme Trouble de la nutrition
Keyword (en)
Adult Narcotic antagonist Drug combination Bupropion Phase III trial Clinical trial Nutritional status Multicenter study Medicine Naltrexone Obesity Weight loss Placebo Body weight Psychotropic Randomization Poison withdrawal Overweight Drug addiction Corporal biometry Morphinan derivatives Human Nutrition disorder
Keyword (es)
Adulto Antagonista narcótico Asociación medicamentosa Bupropión Ensayo clínico fase III Ensayo clínico Estado nutricional Estudio multicéntrico Medicina Naltrexona Obesidad Adelgazamiento Placebo Peso corporal Psicotropo Aleatorización Destete tóxico Sobrecarga ponderal Toxicomanía Biometría corporal Morphinano derivado Hombre Trastorno nutricíon
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B01 General aspects

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B18 Psychopathology. Psychiatry / 002B18C Adult and adolescent clinical studies / 002B18C05 Addictive behaviors / 002B18C05A Drug addiction

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B22 Metabolic diseases / 002B22B Obesity

Francis
770 Psychology. Psychoanalysis. Psychiatry / 770-D Psychopathology. Psychiatry / 770-D03 Adult and adolescent clinical studies / 770-D03E Addictive behaviors / 770-D03E01 Drug addiction

Discipline
Generalities in medical sciences Metabolic diseases Psychopathology. Psychiatry. Clinical psychology
Origin
Inist-CNRS
Database
FRANCIS ; PASCAL
INIST identifier
23157097

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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