Autoantibodies Against the Exocrine Pancreas in Autoimmune Pancreatitis: Gene and Protein Expression Profiling and Immunoassays Identify Pancreatic Enzymes as a Major Target of the I nflammatory Process

Author

LOHR, J.-Matthias^{1 2 3} ; FAISSNER, Ralf¹ ; JESNOWSKI, Ralf^{1 2} ; KADERALI, Lars⁵ ; KLEEFF, Jorg⁸ ; KRUGER, Burkhard⁹ ; LERCH, Markus M¹⁰ ; LÖSEL, Ralf¹¹ ; MAGNANI, Mauro¹² ; NEUMAIER, Michael¹³ ; NITTKA, Stephanie¹³ ; SAHIN-TOTH, Miklós¹⁴ ; KOCZAN, Dirk⁴ ; SÄNGER, Julian¹¹ ; SERAFINI, Sonja¹² ; SCHNÖLZER, Martina¹⁵ ; THIERSE, Hermann-Josef¹⁶ ; WANDSCHNEIDER, Silke¹⁵ ; ZAMBONI, Giuseppe¹⁷ ; KLÖPPEL, Günter¹⁸ ; BEWERUNGE, Peter⁵ ; BASSI, Claudio⁶ ; BRORS, Benedikt⁵ ; EILS, Roland⁵ ; FRULLONI, Luca⁶ ; FUNK, Anette^{1 2} ; HALANGK, Walter⁷
[1] Molecular Gastroenterology, German Cancer Research Center, Heidelberg, Germany
[2] Department of Medicine II, University of Heidelberg, Heidelberg, Germany
[3] Department of Surgical Gastroenterology, Karolinska Institute, Stockholm, Sweden
[4] Department of Immunology, University of Rostock, Rostock, Germany
[5] Department of Theoretical Bioinformatics, German Cancer Research Center, Heidelberg, Germany
[6] Department of Biomedical and Surgical Sciences, University of Verona, Verona, Italy
[7] Department of Surgery, University of Magdeburg, Magdeburg, Germany
[8] Department of Surgery, University of Heidelberg, Heidelberg, Germany
[9] Department of Pathology, University of Rostock, Rostock, Germany
[10] Department of Medicine A, University of Greifswald, Greifswald, Germany
[11] Department of Clinical Pharmacology, University of Heidelberg, Heidelberg, Germany
[12] Institute of Biological Chemistry, University of Urbino, Urbino, Italy
[13] Department of Clinical Chemistry, University of Heidelberg, Heidelberg, Germany
[14] Department of Molecular and Cell Biology, Boston University, Boston, Massachusetts, United States
[15] Functional Proteome Analysis, German Cancer Research Center, Heidelberg, Germany
[16] Department of Dermatology, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany
[17] Department of Pathology, University of Verona, Verona, Italy
[18] Department of Pathology, University of Kiel, Kiel, Germany

Source

The American journal of gastroenterology. 2010, Vol 105, Num 9, pp 2060-2071, 12 p ; ref : 51 ref

ISSN

0002-9270

Scientific domain

Gastroenterology

Publisher

Nature Publishing Group, Basingstoke

Publication country

United Kingdom

Document type

Article

Language

English

Keyword (fr)

Autoanticorps Autoimmunité Expression génique Gastroentérologie Pancréas exocrine Pancréatite Protéine Pathologie de l'appareil digestif Pathologie du pancréas

Keyword (en)

Autoantibody Autoimmunity Gene expression Gastroenterology Exocrine pancreas Pancreatitis Protein Digestive diseases Pancreatic disease

Keyword (es)

Autoanticuerpo Autoinmunidad Expresión genética Gastroenterología Páncreas exocrino Pancreatitis Proteína Aparato digestivo patología Páncreas patología

Classification

Pascal

002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13C Liver. Biliary tract. Portal circulation. Exocrine pancreas / 002B13C03 Other diseases. Semiology

Discipline

Gastroenterology. Liver. Pancreas. Abdomen

Origin

Inist-CNRS

Database

PASCAL

INIST identifier

23199762

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS