Ultrafast and high-throughput mass spectrometric assay for therapeutic drug monitoring of antiretroviral drugs in pediatric HIV-1 infection applying dried blood spots
- Author
- MEESTERS, Roland J. W1 ; VAN KAMPEN, Jeroen J. A1 2 ; REEDIJK, Mariska L2 ; SCHEUER, Rachel D2 ; DEKKER, Lennard J. M1 ; BURGER, David M3 ; HARTWIG, Nico G4 ; OSTERHAUS, Albert D. M. E2 ; LUIDER, Theo M1 ; GRUTERS, Rob A2
[1] Department of Neurology, Laboratory of Neuro-Oncology and Clinical and Cancer Proteomics, University Medical Center Rotterdam (Erasmus MC), Dr. Molewaterplein 50, Room Ee-1981, 3015 GE Rotterdam, Netherlands
[2] Department of Virology, University Medical Center Rotterdam, Dr. Molewaterplein 50, 3015 GE Rotterdam, Netherlands
[3] Department of Clinical Pharmacy, Radboud University Nijmegen Medical Centre, Geert Grooteplein 10, 6525 GA Nijmegen, Netherlands
[4] Department of Paediatrics, Division Infectious Diseases/Immunology, University Medical Center Rotterdam-Sophia Children's Hospital, Dr. Molewaterplein 60, 3015 GJ Rotterdam, Netherlands - Source
Analytical & bioanalytical chemistry (Print). 2010, Vol 398, Num 1, pp 319-328, 10 p ; ref : 30 ref
- ISSN
- 1618-2642
- Scientific domain
- Food science technology; Analytical chemistry; Chemistry
- Publisher
- Springer, Heidelberg
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Dried blood spots HIV-1 Lopinavir MALDI-QqQ-MS/MS Protease inhibitors Ritonavir
- Keyword (fr)
- Acétone Acétonitrile Analyse chimique Application Caractéristique fonctionnement Chromatographie HPLC Concentration Criblage Eau Echantillon Equipement collectif Homme Infection Inhibiteur protease Laboratoire Limite MALDI Monitorage Médicament Mélange Plasma sanguin Préparation échantillon Sang total Spectromètre quadripolaire Spectrométrie masse tandem Spectrométrie masse Traitement Utilisation
- Keyword (en)
- Acetone Acetonitrile Chemical analysis Application Performance characteristic HPLC chromatography Concentration Screening Water Sample Facility Human Infection Protease inhibitor Laboratory Limit Matrix assisted laser desorption ionization Monitoring Drug Mixture Blood plasma Sample preparation Whole blood Quadrupole spectrometer Mass spectrometry MS/MS Mass spectrometry Treatment Use
- Keyword (es)
- Acetona Acetonitrilo Análisis químico Aplicación Característica funcionamiento Cromatografía HPLC Concentración Cernido Agua Muestra Equipamiento colectivo Hombre Infección Inhibidor proteasa Laboratorio Límite MALDI Monitoreo Medicamento Mezcla Plasma sanguíneo Preparación muestreo Sangre total Espectrómetro cuadripolar Espectrometría masa en tándem Espectrometría masa Tratamiento Uso
- Classification
- Pascal
- 001 Exact sciences and technology / 001C Chemistry / 001C04 Analytical chemistry / 001C04B Chromatographic methods and physical methods associated with chromatography / 001C04B02 Other chromatographic methods
- Pascal
- 001 Exact sciences and technology / 001C Chemistry / 001C04 Analytical chemistry / 001C04C Spectrometric and optical methods
- Discipline
- Analytical chemistry
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 23200094
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00216-010-3952-9 
https://dx.doi.org/10.1007/s00216-010-3952-9
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