Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial
- Author
- WALLENTIN, Lars1 ; JAMES, Stefan1 ; BECKER, Richard C1 9 ; STOREY, Robert F2 ; ARMSTRONG, Martin3 ; BARRATT, Bryan J3 ; HORROW, Jay3 ; HUSTED, Steen4 9 ; KATUS, Hugo5 ; GABRIEL STEG, P6 7 8 ; SHAH, Svati H1
[1] Uppsala Clinical Research Centre, Uppsala University, Uppsala, Sweden
[2] Department of Cardiovascular Science, University of Sheffield, Sheffield, United Kingdom
[3] AstraZeneca Research and Development, Alderley Park, United Kingdom
[4] Department of Cardiology, Arhus University Hospital, Arhus, Denmark
[5] Medizinische Klinik, Universitätsklinikum Heidelberg, Heidelberg, Germany
[6] INSERM U-698, Paris, France
[7] Université Paris 7, Paris, France
[8] Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, Paris, France
[9] Duke Clinical Research Institute, Durham, NC, United States
PLATO investigators - Source
Lancet (British edition). 2010, Vol 376, Num 9749, pp 1320-1328, 9 p ; ref : 33 ref
- CODEN
- LANCAO
- ISSN
- 0140-6736
- Scientific domain
- General medicine general surgery
- Publisher
- Elsevier, Kidlington
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Antithrombotique Clopidogrel Essai clinique Etude comparative Evolution Génotype Génétique Inhibiteur thromboagrégation Médecine Polymorphisme mononucléotide Procès Pronostic Ticagrélor Traitement Variabilité génétique Syndrome coronaire aigu Cardiopathie coronaire Dérivé de la thiénopyridine Pathologie de l'appareil circulatoire Pathologie du myocarde
- Keyword (en)
- Antithrombotic agent Clopidogrel Clinical trial Comparative study Evolution Genotype Genetics Antiplatelet agent Medicine Single nucleotide polymorphism Trial Prognosis Ticagrelor Treatment Genetic variability Acute coronary syndrome Coronary heart disease Thienopyridine derivative Cardiovascular disease Myocardial disease
- Keyword (es)
- antitrombōtico Clopidogrel Ensayo clínico Estudio comparativo Evolución Genotipo Genética Inhibidor tromboagregación Medicina Polimorfismo mononucleótido Pronóstico Ticagrelor Tratamiento Variabilidad genética Síndrome coronario agudo Cardiopatía coronaria Tienopiridina derivado Aparato circulatorio patología Miocardio patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B12 Cardiology. Vascular system / 002B12A Heart / 002B12A03 Coronary heart disease
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B12 Cardiology. Vascular system / 002B12A Heart / 002B12A05 Myocarditis. Cardiomyopathies
- Discipline
- Cardiology. Circulatory system Generalities in medical sciences
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 23336433
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0140-6736(10)61274-3 
https://dx.doi.org/10.1016/S0140-6736(10)61274-3
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