In vitro phase I metabolism of the synthetic cannabimimetic JWH-018
- Author
- WINTERMEYER, Annette1 ; MÖLLER, Ines2 ; THEVIS, Mario2 ; JÜBNER, Martin1 ; BEIKE, Justus1 ; ROTHSCHILD, Markus A1 ; BENDER, Katja1
[1] Institute of Legal Medicine, Medical Faculty, University of Cologne, Melatengürtel 60-62, 50823 Cologne, Germany
[2] Center for Preventive Doping Research, Institute of Biochemistry, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933 Cologne, Germany - Source
Analytical & bioanalytical chemistry (Print). 2010, Vol 398, Num 5, pp 2141-2153, 13 p ; ref : 23 ref
- ISSN
- 1618-2642
- Scientific domain
- Food science technology; Analytical chemistry; Chemistry
- Publisher
- Springer, Heidelberg
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Cannabimimetics High-performance liquid chromatography-tandem mass spectrometry Hydroxylation JWH-018 Phase I metabolites
- Keyword (fr)
- Agoniste Alkyle Arène Chromatographie phase liquide Cytochrome P450 Déshydratation Foie Groupe hydroxyle Homme In vitro Indole Molécule Médicament Métabolisme Métabolite Naphtalène Oxydation Pharmacocinétique Spectrométrie masse tandem Toxicité Utilisation
- Keyword (en)
- Agonist Alkyl Arene Liquid chromatography Cytochrome P450 Dehydration Liver Hydroxyl group Human In vitro Indole Molecules Drug Metabolism Metabolite Naphthalene Oxidation Pharmacokinetics Mass spectrometry MS/MS Toxicity Use
- Keyword (es)
- Agonista Alquilo Areno Cromatografía fase líquida Citocromo P450 Deshidratación Hígado Grupo hidróxilo Hombre In vitro Indol Molécula Medicamento Metabolismo Metabolito Naftaleno Oxidación Farmacocinética Espectrometría masa en tándem Toxicidad Uso
- Classification
- Pascal
- 001 Exact sciences and technology / 001C Chemistry / 001C04 Analytical chemistry / 001C04B Chromatographic methods and physical methods associated with chromatography / 001C04B02 Other chromatographic methods
- Pascal
- 001 Exact sciences and technology / 001C Chemistry / 001C04 Analytical chemistry / 001C04C Spectrometric and optical methods
- Discipline
- Analytical chemistry
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 23366831
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00216-010-4171-0 
https://dx.doi.org/10.1007/s00216-010-4171-0
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