Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33
- Author
- HOULSTON, Richard S1 ; CHEADLE, Jeremy2 ; PRENDERGAST, James G. D3 ; PITTMAN, Alan M1 ; THEODORATOU, Evi3 ; SMITH, Christopher G2 ; OLVER, Bianca1 ; WALTHER, Axel4 ; BARNETSON, Rebecca A3 ; CHURCHMAN, Michael4 ; JAEGER, Emma E. M4 ; PENEGAR, Steven1 ; DOBBINS, Sara E1 ; BARCLAY, Ella4 ; MARTIN, Lynn4 ; GORMAN, Maggie4 ; MAGER, Rachel5 ; JOHNSTONE, Elaine5 ; MIDGLEY, Rachel5 ; NIITTYMÄKI, Iina6 ; TUUPANEN, Sari6 ; COLLEY, James2 ; IDZIASZCZYK, Shelley2 ; TENESA, Albert3 ; THOMAS, Huw J. W7 ; LUCASSEN, Anneke M8 ; EVANS, D. Gareth R9 ; MAHER, Eamonn R10 ; MAUGHAN, Timothy11 ; DIMAS, Antigone12 4 ; DERMITZAKIS, Emmanouil12 ; CAZIER, Jean-Baptiste4 ; AALTONEN, Lauri A6 ; PHAROAH, Paul13 ; JONES, Angela M4 ; KERR, David J14 5 ; CARVAJAL-CARMONA, Luis G4 ; CAMPBELL, Harry15 ; DUNLOP, Malcolm G3 ; TOMLINSON, Ian P. M4 ; HOWARTH, Kimberley4 ; SPAIN, Sarah L4 ; BRODERICK, Peter1 ; DOMINGO, Enric4 ; FARRINGTON, Susan3
[1] Section of Cancer Genetics, Institute of Cancer Research, Sutton, United Kingdom
[2] Institute of Medical Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom
[3] Colon Cancer Genetics Group, Institute of Genetics and Molecular Medicine, University of Edinburgh and Medical Research Council Human Genetics Unit, Edinburgh, United Kingdom
[4] Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom
[5] Department of Clinical Pharmacology, Oxford University, Radcliffe Infirmary, Old Road Campus Research Building, Headington, Oxford, United Kingdom
[6] Department of Medical Genetics, Genome-Scale Biology Research Program, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland
[7] Colorectal Cancer Unit, Cancer Research UK, St. Mark's Hospital, Harrow, United Kingdom
[8] Wessex Clinical Genetics Service, Princess Anne Hospital, Southampton, United Kingdom
[9] Medical Genetics, St. Mary's Hospital, Manchester, United Kingdom
[10] Department of Medical and Molecular Genetics, School of Clinical and Experimental Medicine, University of Birmingham, Institute of Biomedical Research and West Midlands Regional Genetics Service, Birmingham Women's Hospital, Edgbaston, Birmingham, United Kingdom
[11] Department of Oncology and Palliative Care, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom
[12] Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland
[13] Cancer Research UK Laboratories, Strangeways Research Laboratory Department of Oncology, University of Cambridge, Cambridge, United Kingdom
[14] Sidra Medical and Research Center, Qatar Foundation, Doha, Qatar
[15] Public Health Sciences, University of Edinburgh, Edinburgh, United Kingdom - Source
Nature genetics. 2010, Vol 42, Num 11, pp 973-977, 5 p ; ref : 8 ref
- Publisher
- Nature Publishing Group, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Cancer colorectal Carte génétique Identification Locus Métaanalyse Association génétique Echelle du génome Cancer Pathologie de l'appareil digestif Pathologie de l'intestin Pathologie du côlon Pathologie du rectum Tumeur maligne
- Keyword (en)
- Colorectal cancer Genetic mapping Identification Locus Metaanalysis Cancer Digestive diseases Intestinal disease Colonic disease Rectal disease Malignant tumor
- Keyword (es)
- Cancer de colon y recto Mapa genético Identificación Locus Meta-análisis Cáncer Aparato digestivo patología Intestino patología Colón patología Recto patología Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A07 Genetics of eukaryotes. Biological and molecular evolution / 002A07C Classical genetics, quantitative genetics, hybrids / 002A07C04 Methods, theories and miscellaneous
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13B Stomach. Duodenum. Small intestine. Colon. Rectum. Anus / 002B13B01 Tumors
- Discipline
- Eukaryotes genetics. Biological and molecular evolution Gastroenterology. Liver. Pancreas. Abdomen
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 23404653
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/ng.670 
https://dx.doi.org/10.1038/ng.670
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arXiv access
