Ligand-induced changes in hepatitis C virus NS5B polymerase structure
- Author
- RIGAT, Karen1 ; YI WANG1 ; HUDYMA, Thomas W2 ; MIN DING2 ; XIAOFAN ZHENG2 ; GENTLES, Robert G2 ; BENO, Brett R3 ; MIN GAO1 ; ROBERTS, Susan B1
[1] Department of Virology, Bristol-Myers Squibb Co., Research & Development, Wallingford, CT 06492, United States
[2] Department of Early Discovery Chemistry, Bristol-Myers Squibb Co., Research & Development, Wallingford, CT 06492, United States
[3] Department of Computer-Assisted Drug Design, Bristol-Myers Squibb Co., Research & Development, Wallingford, CT 06492, United States - Source
Antiviral research. 2010, Vol 88, Num 2, pp 197-206, 10 p ; ref : 1 p
- CODEN
- ARSRDR
- ISSN
- 0166-3542
- Scientific domain
- Microbiology, infectious diseases; Pharmacology drugs; Virology
- Publisher
- Elsevier, Kidlington
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Hepatitis C virus NS5B polymerase Trypsin digest
- Keyword (fr)
- Conformation Ligand Méthode étude RNA-directed RNA polymerase Structure moléculaire Trypsin Virus hépatite C Enzyme Flaviviridae Hepacivirus Hydrolases Infection Nucleotidyltransferases Pathologie de l'appareil digestif Pathologie du foie Peptidases Serine endopeptidases Transferases Virose Virus
- Keyword (en)
- Conformation Ligand Investigation method RNA-directed RNA polymerase Molecular structure Trypsin Hepatitis C virus Enzyme Flaviviridae Hepacivirus Hydrolases Infection Nucleotidyltransferases Digestive diseases Hepatic disease Peptidases Serine endopeptidases Transferases Viral disease Virus
- Keyword (es)
- Conformación Ligando Método estudio RNA-directed RNA polymerase Estructura molecular Trypsin Hepatitis C virus Enzima Flaviviridae Hepacivirus Hydrolases Infección Nucleotidyltransferases Aparato digestivo patología Hígado patología Peptidases Serine endopeptidases Transferases Virosis Virus
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A05 Microbiology / 002A05C Virology / 002A05C08 Action of physical and chemical agents
- Discipline
- Microbiology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 23404843
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/j.antiviral.2010.08.014 
https://dx.doi.org/10.1016/j.antiviral.2010.08.014
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