Effect of VX-770 in Persons with Cystic Fibrosis and the G551D-CFTR Mutation
- Author
- ACCURSO, Frank J1 ; ROWE, Steven M2 ; MOSS, Richard B9 ; PILEWSKI, Joseph M10 ; RUBENSTEIN, Ronald C11 ; ULUER, Ahmet Z12 ; AITKEN, Moira L14 ; FREEDMAN, Steven D13 ; ROSE, Lynn M14 15 ; MAYER-HAMBLETT, Nicole14 15 ; QUNMING DONG16 ; JIUHONG ZHA16 ; CLANCY, J. P2 ; STONE, Anne J16 ; OLSON, Eric R16 ; ORDONEZ, Claudia L16 ; CAMPBELL, Preston W17 ; ASHLOCK, Melissa A17 ; RAMSEY, Bonnie W15 ; BOYLE, Michael P3 ; DUNITZ, Jordan M4 ; DURIE, Peter R5 ; SAGEL, Scott D1 ; HORNICK, Douglas B6 ; KONSTAN, Michael W7 ; DONALDSON, Scott H8
[1] University of Colorado Denver and Children's Hospital, Aurora, United States
[2] University of Alabama at Birmingham, Birmingham, United States
[3] Johns Hopkins Medical Institutions, Baltimore, United States
[4] University of Minnesota, Minneapolis, United States
[5] Hospital for Sick Children and the University of Toronto, Toronto, Canada
[6] University of Iowa Carver College of Medicine, Iowa City, United States
[7] Rainbow Babies and Children's Hospital and Case Western Reserve University School of Medicine, Cleveland, United States
[8] University of North Carolina at Chapel Hill, Chapel Hill, United States
[9] Stanford University School of Medicine, Palo Alto, CA, United States
[10] University of Pittsburgh, Pittsburgh, United States
[11] Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, United States
[12] Children's Hospital Boston, United States
[13] Beth Israel Deaconess Medical Center, Boston, United States
[14] University of Washington, United States
[15] Seattle Children's Hospital, Seattle, United States
[16] Vertex Pharmaceuticals, Cambridge, MA, United States
[17] Cystic Fibrosis Foundation Therapeutics, Bethesda, MD, United States - Source
The New England journal of medicine. 2010, Vol 363, Num 21, pp 1991-2003, 13 p ; ref : 19 ref
- CODEN
- NEJMAG
- ISSN
- 0028-4793
- Scientific domain
- General medicine general surgery
- Publisher
- Massachusetts Medical Society, Waltham, MA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Génétique Mucoviscidose Mutation Médecine Régulateur conductance transmembranaire mucoviscidose Maladie héréditaire Maladie métabolique Pathologie de l'appareil digestif Pathologie de l'appareil respiratoire Pathologie du pancréas
- Keyword (en)
- Genetics Cystic fibrosis Mutation Medicine Cystic fibrosis transmembrane conductance regulator Genetic disease Metabolic diseases Digestive diseases Respiratory disease Pancreatic disease
- Keyword (es)
- Genética Mucoviscidosis Mutación Medicina Regulator conductancia transmembrana mucoviscidosis Enfermedad hereditaria Metabolismo patología Aparato digestivo patología Aparato respiratorio patología Páncreas patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B22 Metabolic diseases / 002B22D Errors of metabolism / 002B22D05 Miscellaneous hereditary metabolic disorders
- Discipline
- Generalities in medical sciences Metabolic diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 23437290
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1056/NEJMoa0909825 
https://dx.doi.org/10.1056/NEJMoa0909825
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