CIP2A mediates effects of bortezomib on phospho-Akt and apoptosis in hepatocellular carcinoma cells

Author

CHEN, K.-F^{1 2} ; LIU, C.-Y^{3 4} ; LIN, Y.-C⁵ ; YU, H.-C^{1 2} ; LIU, T.-H^{1 2} ; HOU, D.-R⁶ ; CHEN, P.-J^{1 2} ; CHENG, A.-L^{2 7 8}
[1] Departments of Medical Research, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, Province of China
[2] National Center of Excellence for Clinical Trial and Research, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, Province of China
[3] Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Province of China
[4] School of Medicine, National Yang-Ming University, Taipei, Taiwan, Province of China
[5] Department of Internal Medicine, Far Eastern Memorial Hospital, Taipei, Taiwan, Province of China
[6] Department of Chemistry, National Central University, Taoyuan, Taiwan, Province of China
[7] Departments of Oncology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, Province of China
[8] Departments of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan, Province of China

Source

Oncogene (Basingstoke). 2010, Vol 29, Num 47, pp 6257-6266, 10 p ; ref : 3/4 p

ISSN

0950-9232

Scientific domain

Cell biology, histology; Medical oncology; Genetics

Publisher

Nature Publishing Group, Basingstoke

Publication country

United Kingdom

Document type

Article

Language

English

Author keyword

CIP2A HCC PP2A apoptosis bortezomib proteasome inhibitor

Keyword (fr)

Akt protein kinase Anticancéreux Apoptose Bortézomib Carcinogenèse Carcinome hépatocellulaire Inhibiteur Multicatalytic endopeptidase complex Cancer Enzyme Hydrolases Pathologie de l'appareil digestif Pathologie du foie Peptidases Tumeur maligne

Keyword (en)

Akt protein kinase Antineoplastic agent Apoptosis Bortezomib Carcinogenesis Hepatocellular carcinoma Inhibitor Multicatalytic endopeptidase complex Cancer Enzyme Hydrolases Digestive diseases Hepatic disease Peptidases Malignant tumor

Keyword (es)

Akt protein kinase Anticanceroso Apoptosis Bortezomib Carcinogénesis Carcinoma hepatocelular Inhibidor Multicatalytic endopeptidase complex Cáncer Enzima Hydrolases Aparato digestivo patología Hígado patología Peptidases Tumor maligno

Classification

Pascal

002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H04 Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes

Pascal

002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H05 Ageing, cell death

Pascal

002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13C Liver. Biliary tract. Portal circulation. Exocrine pancreas / 002B13C01 Tumors

Discipline

Gastroenterology. Liver. Pancreas. Abdomen Molecular and cell biology

Origin

Inist-CNRS

Database

PASCAL

INIST identifier

23629993

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS