Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor
- Author
- RESSLER, Kerry J1 2 4 ; MERCER, Kristina B1 ; RAMIREZ, Manuel5 ; ENGEL, Anzhelika5 ; HAMMACK, Sayamwong E6 ; TOUFEXIS, Donna4 6 ; BRAAS, Karen M7 ; BINDER, Elisabeth B2 8 ; MAY, Victor7 ; BRADLEY, Bekh2 3 ; JOVANOVIC, Tanja2 ; MAHAN, Amy4 ; KERLEY, Kimberly1 ; NORRHOLM, Seth D2 3 ; KILARU, Varun2 ; SMITH, Alicia K2 ; MYERS, Amanda J5
[1] Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, United States
[2] Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia 30322, United States
[3] Atlanta VA Medical Center, Atlanta, Georgia 30033, United States
[4] Yerkes National Primate Research Center, Atlanta, Georgia 30329, United States
[5] University of Miami, Miller School of Medicine, Miami, Florida 33136, United States
[6] Department of Psychology, University of Vermont, Burlington, Vermont 05401, United States
[7] Departments of Anatomy and Neurobiology and Pharmacology, University of Vermont College of Medicine, Burlington, Vermont 05401, United States
[8] Max Planck Institute of Psychiatry, Munich 80804, Germany - Source
Nature (London). 2011, Vol 470, Num 7335, pp 492-497, 6 p ; ref : 41 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Amygdale Animal Etat de stress posttraumatique Expression génique Femme Modèle animal Méthylation Noyau amygdalien Noyau du lit de la strie terminale Oestrogène Peptide PACAP Peur Polymorphisme mononucléotide RNA messager Rat Récepteur PAC1 Régulation neuroendocrinienne Souris Stress Affect affectivité Déterminisme génétique Encéphale Génétique Homme Hormone ovarienne Hormone stéroïde sexuelle Mammalia Neuropeptide Noyau gris central Rodentia Système nerveux central Trouble anxieux Vertebrata
- Keyword (en)
- Amygdala Animal Posttraumatic stress disorder Gene expression Woman Animal model Methylation Amygdaloid nucleus Bed nucleus of the stria terminalis Estrogen Pituitary adenylate cyclase activating peptide Fear Single nucleotide polymorphism Messenger RNA Rat PAC1 receptor Neuroendocrine regulation Mouse Stress Affect affectivity Genetic determinism Encephalon Genetics Human Ovarian hormone Sex steroid hormone Mammalia Neuropeptide Basal ganglion Rodentia Central nervous system Anxiety disorder Vertebrata
- Keyword (es)
- Amígdala Animal Trastorno de estrés posttraumático Expresión genética Mujer Modelo animal Metilación Núcleo amigdalino Núcleo estría terminal Estrógeno Péptido PACAP Miedo Polimorfismo mononucleótido RNA mensajero Rata Receptor PAC1 Regulación neuroendocrina Ratón Estrés Afecto afectividad Determinismo genético Encéfalo Genética Hombre Hormona ovárica Hormona esteroide sexual Mammalia Neuropéptido Núcleo basal Rodentia Sistema nervioso central Trastorno ansiedad Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B18 Psychopathology. Psychiatry / 002B18C Adult and adolescent clinical studies / 002B18C08 Anxiety disorders. Neuroses / 002B18C08D Post-traumatic stress disorder
- Francis
- 770 Psychology. Psychoanalysis. Psychiatry / 770-D Psychopathology. Psychiatry / 770-D03 Adult and adolescent clinical studies / 770-D03H Anxiety disorders. Neuroses / 770-D03H04 Post-traumatic stress disorder
- Discipline
- Psychopathology. Psychiatry. Clinical psychology
- Origin
- Inist-CNRS
- Database
- FRANCIS ; PASCAL
- INIST identifier
- 23873067
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/nature09856 
https://dx.doi.org/10.1038/nature09856
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