Common variants in DGKK are strongly associated with risk of hypospadias
- Author
- VAN DER ZANDEN, Loes F. M1 2 ; VAN ROOIJ, Iris A. L. M1 ; ARIAS-VASQUEZ, Alejandro2 6 ; XUFENG ZHANG7 ; MARKLJUNG, Ellen7 ; LIANG QIAO8 ; BASKIN, Laurence S8 ; NORDENSKJÖLD, Agneta7 9 ; ROELEVELD, Nel1 ; FRANKE, Barbara2 6 ; KNOERS, Nine V.a M2 ; FEITZ, Wout F. J3 ; KNIGHT, Jo4 5 ; DONDERS, A. Rogier T1 ; RENKEMA, Kirsten Y2 ; BONGERS, Ernie M. H. F2 ; VERMEULEN, Sita H.h M1 2 ; KIEMENEY, Lambertus A. L. M1 3 ; VELTMAN, Joris A2
[1] Department of Epidemiology, Biostatistics and HTA, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
[2] Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
[3] Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
[4] Division of Genetics and Molecular Medicine, King's College London School of Medicine, London, United Kingdom
[5] National Institute for Health Research (NIHR), Biomedical Research Centre, Guy's and St. Thomas' National Health Service (NHS) Foundation Trust and King's College London, London, United Kingdom
[6] Department of Psychiatry, Donders Institute for Brain, Cognition and Behavior, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
[7] Department of Women's and Children's Health and Center of Molecular Medicine, Karolinska Institutet, Stockholm, Sweden
[8] Department of Urology, University of California, San Francisco, California, United States
[9] Department of Pediatric Surgery, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden - Source
Nature genetics. 2011, Vol 43, Num 1, pp 48-50, 3 p ; ref : 19 ref
- Publisher
- Nature Publishing Group, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Hypospadias Risque Variant Malformation Pathologie de l'appareil urinaire Pathologie de l'urètre Pathologie des voies urinaires
- Keyword (en)
- Hypospadias Risk Variant Malformation Urinary system disease Urethral disease Urinary tract disease
- Keyword (es)
- Hipospadias Riesgo Variante Malformación Aparato urinario patología Uretra patología Vía urinaria patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A07 Genetics of eukaryotes. Biological and molecular evolution
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B14 Nephrology. Urinary tract diseases / 002B14C Malformations of the urinary system / 002B14C02 Urinary tract. Prostate gland
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B20 Gynecology. Andrology. Obstetrics / 002B20B Male genital diseases / 002B20B01 Non tumoral diseases
- Discipline
- Eukaryotes genetics. Biological and molecular evolution Gynecology. Andrology. Obstetrics Nephrology. Urinary tract diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 23919048
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/ng.721 
https://dx.doi.org/10.1038/ng.721
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