Mechanisms of T-cell protection from death by IRX-2: a new immunotherapeutic
- Author
- CZYSTOWSKA, Malgorzata1 ; SZCZEPANSKI, Miroslaw J1 ; SZAJNIK, Marta1 ; QUADRINI, Karen2 ; BRANDWEIN, Harvey2 ; HADDEN, John W2 ; WHITESIDE, Theresa L1
[1] Research Pavilion at the Hillman Cancer Center, University of Pittsburgh Cancer Institute, 5117 Centre Avenue, Suite 1.27, Pittsburgh, PA 15213-1863, United States
[2] IRX Therapeutics, Inc, 1 Bioscience Park Drive, Farmingdale, NY 11735, United States - Source
Cancer immunology and immunotherapy. 2011, Vol 60, Num 4, pp 495-506, 12 p ; ref : 34 ref
- CODEN
- CIIMDN
- ISSN
- 0340-7004
- Scientific domain
- Biochemistry, molecular biology, biophysics; Medical oncology; Immunology, immunopathology, allergology
- Publisher
- Springer, Heidelberg
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Apoptosis Bcl-2 proteins IRX-2 Lymphocyte survival PI3K/Akt Tumor-derived exosomes cFLIP
- Keyword (fr)
- 1-Phosphatidylinositol 3-kinase Akt protein kinase Apoptose Gène onc cellulaire Immunothérapie Lymphocyte T Mort cellulaire Mécanisme action Protooncogène Protéine Survie Traitement Tumeur maligne Exosome Gène bcl2 Cancer Enzyme Transferases
- Keyword (en)
- 1-Phosphatidylinositol 3-kinase Akt protein kinase Apoptosis C-Onc gene Immunotherapy T-Lymphocyte Cell death Mechanism of action Protooncogene Protein Survival Treatment Malignant tumor Exosome Cancer Enzyme Transferases
- Keyword (es)
- 1-Phosphatidylinositol 3-kinase Akt protein kinase Apoptosis Gen onc celular Inmunoterapia Linfocito T Muerte celular Mecanismo acción Protooncogen Proteína Sobrevivencia Tratamiento Tumor maligno Exosoma Cáncer Enzima Transferases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R03 Immunotherapy
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 24021981
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00262-010-0951-9 
https://dx.doi.org/10.1007/s00262-010-0951-9
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