Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice
- Author
- KIEFER, F. W1 ; NESCHEN, S2 ; PLUTZKY, J4 ; ZEYDA, M1 ; STULNIG, T. M1 ; PFAU, B1 ; LEGERER, B1 ; NEUHOFER, A1 ; KAHLE, M2 ; HRABE DE ANGELIS, M2 ; SCHLEDERER, M3 ; MAIR, M3 ; KENNER, L3
[1] Department of Medicine III, Clinical Division of Endocrinology and Metabolism, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria
[2] Institute of Experimental Genetics, Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg, Germany
[3] Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria
[4] Department of Medicine, Brigham and Women's Hospital Boston, Cardiovascular Division, Harvard Medical School, Boston, MA, United States - Source
Diabetologia (Berlin). 2011, Vol 54, Num 8, pp 2132-2142, 11 p ; ref : 46 ref
- ISSN
- 0012-186X
- Scientific domain
- Endocrinology; Nutrition, obesity, metabolic disorders
- Publisher
- Springer, Heidelberg
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Author keyword
- Gluconeogenesis High-fat diet Inflammation Insulin resistance Non-alcoholic fatty liver disease
- Keyword (fr)
- Animal Diabète Déficit Etat nutritionnel Gluconéogenèse Glucose Inflammation Insulinorésistance Obésité Ostéopontine Régime alimentaire Souris Stéatohépatite non alcoolique Stéatose hépatique Alimentation Endocrinopathie Maladie métabolique Mammalia Pathologie de l'appareil digestif Pathologie du foie Rodentia Résistance tissu cible Trouble de la nutrition Vertebrata
- Keyword (en)
- Animal Diabetes mellitus Deficiency Nutritional status Gluconeogenesis Glucose Inflammation Insulin resistance Obesity Osteopontin Diet Mouse Non alcoholic steatohepatitis Fatty liver Feeding Endocrinopathy Metabolic diseases Mammalia Digestive diseases Hepatic disease Rodentia Target tissue resistance Nutrition disorder Vertebrata
- Keyword (es)
- Animal Diabetes Déficiencia Estado nutricional Gluconeogénesis Glucosa Inflamación Resistancia insulina Obesidad Osteopontina Régimen alimentario Ratón Esteatohepatitis no alcohólica Hígado graso Alimentación Endocrinopatía Metabolismo patología Mammalia Aparato digestivo patología Hígado patología Rodentia Resistencia tejido blanco Trastorno nutricíon Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13C Liver. Biliary tract. Portal circulation. Exocrine pancreas / 002B13C03 Other diseases. Semiology
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B21 Endocrinopathies / 002B21E Endocrine pancreas. Apud cells (diseases) / 002B21E01 Diabetes. Impaired glucose tolerance / 002B21E01A Etiopathogenesis. Screening. Investigations. Target tissue resistance
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B22 Metabolic diseases / 002B22B Obesity
- Discipline
- Endocrinopathies Gastroenterology. Liver. Pancreas. Abdomen Metabolic diseases
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 24332770
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00125-011-2170-0 
https://dx.doi.org/10.1007/s00125-011-2170-0
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